| 常用名 | JNJ28871063 hydrochloride | CAS号 | 944342-90-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: JNJ28871063 hydrochloride is an orally active, highly selective and ATP competitive pan-ErbB kinase inhibitor with IC50 values of 22 nM, 38 nM, and 21 nM for ErbB1, ErbB2, and ErbB4, respectively. JNJ28871063 hydrochloride inhibits phosphorylation of functionally important tyrosine residues in both EGFR and ErbB2. JNJ28871063 hydrochloride crosses the blood-brain barrier and has antitumor activity in human tumor xenograft models that overexpress EGFR and ErbB2[1]. 物理化学性质: CAS号:944342-90-9 常用中文名:JNJ28871063 hydrochloride 常用英文名:JNJ 28871063 hydrochloride 分子式:C24H28Cl2N6O3 分子量:519.42400 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |