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55366-56-8

55366-56-8结构式

中文名	棉皮素-8-O-β-D-葡萄糖醛酸苷
英文名	(2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxochromen-8-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
中文别名	(2S,3S,4S,5R,6S)-6-((2-(3,4-二羟基苯基)-3,5,7-三羟基-4-氧代-4H-苯并吡喃-8-基)氧基)-3,4,5-三羟基四氢-2H-吡喃-2-甲酸棉黄素8-O-BETA-D-葡糖苷酸棉花皮素-8-O-葡萄糖醛酸苷棉子素杂质2(棉子素8-O-Β-D-葡糖苷酸) 棉皮素-8-O-Β-D-葡萄糖醛酸苷棉黄素-Β-D-葡萄糖苷酸
英文别名	Hibifolin，Gossypetin-8-O-β-D-glucuronid Gossypetin -beta-D-glucuronide hibifolin Gossypetin-8-O-β-D-glucuronide, Hibifoli Hibifolin-RM Gossypetin-8-O-β-D-glucuronide Gossypetin Impurity 2(Gossypetin 8-O-beta-D-glucuronide) Adenosine Deaminase,Hibifolin,adenosine,anti-proliferative,anti-inflammatory,neurotoxicity,Inhibitor,deaminase,inhibit Hibifolin， Gossypetin-8-O-β-D-glucuronide Hibifolin (Gossypetin 8-O-beta-D-glucuronide) β-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl [2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl]β-D-glucopyranosiduronic acid Gossypetin 8-O-beta-D-glucuronide Gossypetin-8-glucuronide (2S,3S,4S,5R,6S)-6-((2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-chromen-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-cboxylic acid Gossypetin-8-O-β-D-glucuronide, Hibifolin

描述	Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶 (ADA) 抑制剂。Hibifolin 可以保护神经元免受 beta-淀粉样蛋白诱导的神经毒性。
相关类别	研究领域 >> 癌症研究领域 >> 炎症/免疫研究领域 >> 神经疾病信号通路 >> 代谢酶/蛋白酶 >> 腺苷脱氨酶
靶点	Ki: 49.92 μM (ADA)[1]
参考文献	[1]. K G Arun, et al. Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study. Comput Biol Chem. 2016 Oct;64:353-358. [2]. Judy T T Zhu, et al. Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2009 Sep 18;461(2):172-6.