214193-11-0

• 常用中文名：(1S,3S,5S)-N-BOC-2-氮杂双环[3.1.0]己烷-3-甲酸乙酯
• 常用英文名：(1S,3S,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
• CAS号：214193-11-0
• 分子式：C₁₃H₂₁NO₄
• 分子量：255.31000
• 发布时间：2016-04-16 04:55:48
• 更新时间：2025-08-26 19:12:19

名称

• 中文名: (1S,3S,5S)-N-BOC-2-氮杂双环[3.1.0]己烷-3-甲酸乙酯
• 英文名: 2-O-tert-butyl 3-O-ethyl (3S)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
• 中文别名: 沙格列汀杂质7; (1S,3S,5S)-2-氮杂双环[3.1.0]己烷-2,3-二甲酸酯; 沙格列汀杂质49; (1S,3S,5S)-2-叔丁基3-乙基2-氮杂双环[3.1.0]己烷-2,3-二羧酸酯; 3-乙基; 2-叔丁基; O2-叔丁基O3-乙基(1S,3S,5S)-2-氮杂双环[3.1.0]己烷-2,3-二羧酸酯; 英文名称2-AZABICYCLO[3.1.0]HEXANE-2,3-DICBOXYLIC ACID, 2-(1,1-DIMETHYLETHYL) 3-ETHYL ESTER, (1S,3S,5S); 沙格列汀杂质42
• 英文别名: O2-tert-butyl O3-ethyl (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicboxylate; 2-Azabicyclo[3.1.0]hexane-2,3-dicboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1S,3S,5S); Saxagliptin Impurity 49; ethyl (1s,3s,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-cboxylate; (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-2,3-dicboxylic Acid 2-(1,1-Dimethylethyl) 3-ethyl Ester; Ethyl (1S,3S,5S)-N-Boc-2-azabicyclo[3.1.0]hexane-3-cboxylate; 2-O-Tert-butyl 3-O-ethyl (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicboxylate; N-Boc-L-cis-4,5-methanoproline ethyl ester; (1S,3S,5S)-2-TERT-BUTYL 3-ETHYL 2-AZABICYCLO[3.1.0]HEXANE-2,3-DICARBOXYLATE; 2-tert-butyl 3-ethyl (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicboxylate; (1S,3S,5S)-2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester 3-ethyl ester; (s)-BOC-4,5-methanoproline ethyl ester

物化性质

• 分子式: C₁₃H₂₁NO₄
• 分子量: 255.31000
• 精确质量: 255.14700
• PSA: 55.84000
• LogP: 1.88530

合成路线

593-71-5 178172-26-4 ~40% 214193-11-0

文献：ALANTOS PHARMACEUTICALS, INC. Patent: WO2006/116157 A2, 2006 ; Location in patent: Page/Page column 114-115 ; WO 2006/116157 A2

75-11-6 178172-26-4 ~% 214193-11-0

文献：ACTELION PHARMACEUTICALS LTD Patent: WO2008/81399 A2, 2008 ; Location in patent: Page/Page column 85 ; WO 2008/081399 A2

144978-35-8 ~% 214193-11-0

文献：Hanessian, Stephen; Reinhold, Ulrich; Saulnier, Michel; Claridge, Stephen Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2123 - 2128

194594-23-5 ~% 214193-11-0

文献：Hanessian, Stephen; Reinhold, Ulrich; Saulnier, Michel; Claridge, Stephen Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2123 - 2128

194594-24-6 ~% 214193-11-0

文献：Hanessian, Stephen; Reinhold, Ulrich; Saulnier, Michel; Claridge, Stephen Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2123 - 2128

178172-26-4 ~% 214193-11-0

文献：Hanessian, Stephen; Reinhold, Ulrich; Saulnier, Michel; Claridge, Stephen Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2123 - 2128

上下游产品

上游产品  6
593-71-5 178172-26-4 75-11-6 144978-35-8
194594-23-5 194594-24-6
下游产品  2
197142-36-2 214193-13-2