85999-40-2

85999-40-2结构式

中文名	23-羟基白桦酸
英文名	(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aS,13bR)-9-hydroxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
英文别名	(3β,13α)-3,23-Dihydroxylup-20(29)-en-28-oic acid Lup-20(29)-en-28-oic acid, 3,23-dihydroxy-, (3β,13α)- Anemosapogenin (3β)-3,23-Dihydroxylup-20(29)-en-28-oic acid 23-Hydroxybetulinic acid 3\|A,23-Dihydroxylup-20(29)-en-28-oic acid Lup-20(29)-en-28-oic acid, 3,23-dihydroxy-, (3β)- 23-hydroxy butulinic acid 23-HBA

描述	23-hydroxybetulinic acid是具有抗癌活性的生物化合物。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 癌症天然产物 >> 酸和醛
参考文献	[1]. Liu M et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm Biol. 2015 Jan;53(1):1-9. [2]. Zhang DM et al. BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo. Mol Pharm. 2012 Nov 5;9(11):3147-59. [3]. Zheng Y et al. 23-Hydroxybetulinic acid from Pulsatilla chinensis (Bunge) Regel synergizes the antitumor activities of doxorubicin in vitro and in vivo. J Ethnopharmacol. 2010 Apr 21;128(3):615-22.

密度	1.1±0.1 g/cm3
沸点	585.8±25.0 °C at 760 mmHg
熔点	305 °C
分子式	C₃₀H₄₈O₄
分子量	472.700
闪点	322.1±19.7 °C
精确质量	472.355255
PSA	77.76000
LogP	7.29
外观性状	固体;White to Light yellow powder to crystal
蒸汽压	0.0±3.7 mmHg at 25°C
折射率	1.543
储存条件	-20°C;存放于惰性气体之中;避免光,湿气 (分解),加热