27292-49-5

• 常用中文名：3-吗啉苯酚
• 常用英文名：3-(4-Morpholinyl)phenol
• CAS号：27292-49-5
• 分子式：C₁₀H₁₃NO₂
• 分子量：179.216
• 发布时间：2018-06-29 12:10:06
• 更新时间：2024-01-03 13:58:59
• 下载msds

名称

• 中文名: 3-(4-吗啉基)苯酚
• 英文名: 3-morpholin-4-ylphenol
• 中文别名: 3-吗啉苯酚
• 英文别名: m-Morpholinophenol; 3-(Morpholin-4-yl)phenol; 3-(4-morpholino)phenol; Phenol, 3-(4-morpholinyl)-; 3-(4-morpholinyl)-phenol; 3-Morpholinophenol; MFCD00051675; 3-Morpholin-4-yl-phenol; m-N-morpholinophenol; N-(3-Hydroxyphenyl)morpholine; 3-(4-Morpholinyl)phenol

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 362.6±37.0 °C at 760 mmHg
• 熔点: 132ºC
• 分子式: C₁₀H₁₃NO₂
• 分子量: 179.216
• 闪点: 173.1±26.5 °C
• 精确质量: 179.094635
• PSA: 32.70000
• LogP: 0.59
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.575
• 储存条件:

  保持贮藏器密封

  放入紧密的贮藏器内，储存在阴凉，干燥的地方

• 稳定性:

  如果遵照规格使用和储存则不会分解

  避免接触氧化物
• 分子结构:

  1、 摩尔折射率：49.94

  2、 摩尔体积（m³/mol）：151.1

  3、 等张比容（90.2K）：396.2

  4、 表面张力（dyne/cm）：47.2

  5、 极化率（10 ^-24cm ³）：19.79

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:1

  5.互变异构体数量:3

  6.拓扑分子极性表面积32.7

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:157

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状： 未确定

  2. 密度（g/mL,25/4℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：136

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

MSDS

Name: 3-Morpholinophenol 97% Material Safety Data Sheet Synonym: N-(3-Hydroxyphenyl)morpholin CAS: 27292-49-5 Section 1 - Chemical Product MSDS Name:3-Morpholinophenol 97% Material Safety Data Sheet Synonym:N-(3-Hydroxyphenyl)morpholin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 27292-49-5 3-Morpholinophenol 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 27292-49-5: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: pink Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 132 - 134 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H13NO2 Molecular Weight: 179.22 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, acids, bases, acid chlorides. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 27292-49-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 3-Morpholinophenol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 27292-49-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 27292-49-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 27292-49-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微危害的，若无政府许可，勿将材料排入周围环境

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36
• 海关编码: 2934999090

合成路线

26926-56-7 ~80% 27292-49-5

文献：WO2005/123054 A1, ; Page/Page column 30 ;

110-91-8 591-20-8 ~93% 27292-49-5

文献：Advanced Synthesis and Catalysis, , vol. 346, # 6 p. 611 - 616

110-91-8 108-43-0 ~96% 27292-49-5

文献：Advanced Synthesis and Catalysis, , vol. 346, # 6 p. 611 - 616

110-91-8 106-41-2 ~% 27292-49-5 6291-23-2

文献：Organic Letters, , vol. 5, # 19 p. 3515 - 3517

110-91-8 108-46-3 ~% 27292-49-5

文献：DE720167 , ; DRP/DRBP Org.Chem.

111-44-4 591-27-5 ~% 27292-49-5

文献：Industrial and Engineering Chemistry, , vol. 28, p. 656

上下游产品

上游产品  8
26926-56-7 110-91-8 591-20-8 108-43-0
106-41-2 108-46-3 111-44-4 591-27-5
下游产品  3
32040-09-8 70362-07-1 404009-40-1

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%