3870-07-3

• 常用中文名：醋酸曲安奈德
• 常用英文名：Triamcinolone acetonide acetate
• CAS号：3870-07-3
• 分子式：C₂₆H₃₃FO₇
• 分子量：476.534
• 相关类别： 原料药 激素及调节内分泌功能类药 肾上腺皮质激素类药
• 发布时间：2018-02-07 08:00:00
• 更新时间：2026-07-11 16:50:08

名称

• 中文名: 醋酸曲安奈德
• 英文名: 21-(Acetyloxy) Triamcinolone Acetonide
• 中文别名: 16Α,17〔(1-甲基亚乙基)-双(氧)〕-11Β,21-二羟基-9-氟孕甾-1,4-二烯-3,20-二酮-21-醋酸酯; 乙腈中醋酸曲安奈德; 醋酸曲安奈德杂质; 醋酸曲安奈德(API); 醋酸曲安奈德糖皮质激素类药物 醋酸曲安奈德 醋酸曲安奈德; 醋酸曲安奈德/3-3; 曲安奈德杂质7; 甲醇中曲安奈德醋酸酯溶液标准物质; 2-((6AS,6BR,7S,8AS,8BS,11,12AS,12BS)-6B-氟-7-羟基-6A,8A,10,10-四甲基-4-氧代-1,2,4,6A,6B,7,8,8A,11A,12,12A,12B-十二氢-8BH-萘并[2',1':4,5]茚满并[1,2-D][1,3]二氧戊环-8B-基)-2-氧代乙酸乙酯; 醋酸曲安奈德杂质F; 醋酸曲安奈德原料药; 醋酸曲安奈德溶液,100PPM; 曲安西龙杂质F; 曲安奈德丙酮杂质F; 曲安奈德 21-醋酸酯; 曲安奈德杂质F; 醋酸曲安奈德(醋酸曲安缩松); 曲安奈德醋酸酯; 湖北醋酸曲安奈德原料药
• 英文别名: 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3; TriamcinoloneTriamcinolone Acetonide Acetate Acetonide Acetate; 9-Fluoro-11b,21-dihydroxy-16a,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate; C17635100 TriamcinolonEAcetonidE21-Acetate; BNKY017-TA03; 2-((6AS,6bR,7S,8aS,8bS,11,12aS,12bS)-6b-fluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate; Triamcinolone Acetonide Impurity 7; Thannad acetate; GB/-2009 41 Glucocorticoids 100 μg/mL in Methanol; Triamcinolone cinolone Impurity F; 20-dione 21-acetate; 21-(Acetyloxy)-9-fluoro-11β-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; Triamcinolone impurity I; 2-(4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethyl acetate; Triamcinolone aceton; 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate; Triamcinolone Impurity F; Triamcinolone acetonide impurity F (Triamcinolone Acetonide 21-Acetate); TRIAMCINOLONE ACETONIDE ACETATE; 9-Fluoro-11beta-hydroxy-16alpha,17-(1-methylethylidenedioxy)-3,20-dioxopregna-1,4-dien-21-yl Acetate; Triamcinolone acetonide 21-acetate //BP; Triamcinolone Acetonide Impurity 6（Triamcinolone Acetonide Impurity F）; 21-(Acetyloxy) TriaMcinolone Acetonide; Triamcinolon Acetonide acetate; 9-fluoro-11β; (11β,16α)-21-(Acetyloxy)-9-fluoro-11-hydroxy-16,17-[(1-Methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; 9-Fluoro-11beta-hydroxy-16alpha,17-(1-methylethylidenedioxy)-3,20-dioxopregna-1,4-dien-21-yl Acetate (21-Acetate Triamcinolone Acetonide); 9-fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate; (11β,16α,17α)-21-acetyloxy-9-fluoro-11-hydroxy-16,17-(1-methylethylidenebis(oxy))pregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α); Triamcinolone acetonide acetate, Glucocorticoid; Triamcinolone acetonide 21-acetate; Triamcinolone Acetonide EF Impurity F

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 589.4±50.0 °C at 760 mmHg
• 分子式: C₂₆H₃₃FO₇
• 分子量: 476.534
• 闪点: 310.3±30.1 °C
• 精确质量: 476.221039
• PSA: 99.13000
• LogP: 3.61
• 蒸汽压: 0.0±3.8 mmHg at 25°C
• 折射率: 1.570
• 储存条件: 2~8℃

安全

• 危害码 (欧洲): Xi
• 安全声明 (欧洲): 24/25

合成路线

108-24-7 76-25-5 ~% 3870-07-3

文献：Journal of the American Chemical Society, , vol. 80, p. 2338 US3048581 , ;

124-94-7 ~% 3870-07-3

文献：Journal of the American Chemical Society, , vol. 80, p. 2338

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