147118-40-9

• 常用中文名：瑞舒伐他汀中间体H-3
• 常用英文名：Rosuvastatin methyl ester
• CAS号：147118-40-9
• 分子式：C₂₃H₃₀FN₃O₆S
• 分子量：495.564
• 发布时间：2018-03-09 08:00:00
• 更新时间：2024-01-08 06:51:21

名称

• 中文名: 瑞舒伐他汀甲酯
• 英文名: methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
• 中文别名: 罗苏伐他汀甲酯; 7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰氨基)嘧啶-5-基]-3,5－二羟基-6(E)-庚烯酸甲酯
• 英文别名: 7-[4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonyl-methyl-amino)pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester; Methyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate; (+)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl)-(3R,5S,6E)-dihydroxy-hept-6-enoic acid methyl ester; X6287; methyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; Methyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}-3,5-dihydroxy-6-heptenoate; methyl (6E)-7-{4-(4-flurophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}(3R,5S)-3,5-dihydroxyhept-6-enoate; Rosuvastatin methyl ester; (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid methyl ester; methyl (3R,5S,6E)-7-[4-(4-flurophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidyl]-3,5-dihydroxy-6-heptenoate; (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)]-2-[methyl(methylsulfonyl)amino-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid methyl ester; AC-3412; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, methyl ester, (3R,5S,6E)-; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid methyl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 692.3±65.0 °C at 760 mmHg
• 分子式: C₂₃H₃₀FN₃O₆S
• 分子量: 495.564
• 闪点: 372.5±34.3 °C
• 精确质量: 495.183929
• PSA: 138.30000
• LogP: 1.01
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.576
• 储存条件: 室温，干燥密封

安全

• 海关编码: 2935009090

合成路线

上下游产品

上游产品  7
147118-39-6 147118-37-4 147118-38-5 459-57-4
147118-27-2 147118-36-3 147118-28-3
下游产品  3
503610-43-3 287714-41-4 1353050-10-8

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%