147118-40-9

• 常用中文名：瑞舒伐他汀中间体H-3
• 常用英文名：Rosuvastatin methyl ester
• CAS号：147118-40-9
• 分子式：C₂₃H₃₀FN₃O₆S
• 分子量：495.564
• 发布时间：2018-03-09 08:00:00
• 更新时间：2026-07-28 17:16:40

名称

• 中文名: 瑞舒伐他汀甲酯
• 英文名: methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
• 中文别名: 瑞舒伐他汀甲酯(瑞舒伐他汀杂质50); 7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰氨基)嘧啶-5-基]-3,5－二羟基-6(E)-庚烯酸甲酯; 瑞舒伐他汀钙中间体H-3; 罗苏伐他汀甲酯; 瑞舒伐他汀钙 RJS3,7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰氨基)嘧啶-5-基]-3,5-二羟基-6(E)-庚烯酸甲酯; 超级他汀甲酯; 甲基(3R,5S,E)-7-(4-(4-氟苯基)-6-异丙基-2-(N-甲基磺酰氨基)嘧啶-5-基)-3,5-二羟乙基-6-烯酸酯; 瑞舒伐他汀酸甲基酯; (3R,5S,E)-7-(4-(4-氟苯基)-6-异丙基-2-(N-甲基甲磺酰胺基)嘧啶-5-基)-3,5-二羟基庚-6-烯酸甲酯; 瑞舒伐他汀钙中间体RJS3; 舒伐他汀甲酯; RJS-3: 7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰胺)嘧啶-5-基]-(3R, 5R)-二羟基-(E)-6-庚烯酸甲酯; 瑞舒伐他汀钙H-3; 瑞舒伐他汀杂质
• 英文别名: (3R,5S,E)Methyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonylamino)-pyrimidin-5-yl)-3,5-dihydroxyht-6-enoate; Methyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate; Methyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}-3,5-dihydroxy-6-heptenoate; Rosuvastatin Acid Methyl Ester; D36-D; methyl (6E)-7-{4-(4-flurophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}(3R,5S)-3,5-dihydroxyhept-6-enoate; 6-Htenoic acid,7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)amino]-5-pyriMidinyl]-3,5-dihydroxy-,Methyl ester, (3R,5S,6E); (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid methyl ester; (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)]-2-[methyl(methylsulfonyl)amino-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid methyl ester; N-Methyl acetaMidc 7-[4-(4-flucrophenyl)-6-iso-propyl-2-(N-Methyl-N-Methyl sulfonyleMino) pyriMidin-5-yl[ -(3R,5S)-dihydroxy-(e)- 6-hteeoate; Rosuvastatin Impurity 18; AC-3412; Rosuvastatin methyl ester,7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-ht-6-enoic acid methyl ester; Rosuvastatin Calcium Inter; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)amino]-5-pyriMidinyl]-3,5-dihydroxy-6-htenoic Acid Methyl Ester; (3R,5S,E)-methyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyht-6-enoate; 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Htenoic acid methyl ester (3R,5S,6E)- (9CI ACI); 7-[4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonyl-methyl-amino)pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester; 2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyht-6-enoate; 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-ht-6-enoic acid methyl ester; (+)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl)-(3R,5S,6E)-dihydroxy-hept-6-enoic acid methyl ester; X6287; methyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; ROSUVASTATIN METHYL ESTER; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)-amino]-5-pyrimidi; methyl (3R,5S,6E)-7-[4-(4-flurophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidyl]-3,5-dihydroxy-6-heptenoate; methyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyht-6-enoate; methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyht-6-enoate; Methyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyht-6-enoate; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)-amino]-5-pyrimidinyl; ROSUVASTATIN CALCIUM INTERMEDIATE (RJS3); Rosuvastatin methyl este; 6-Htenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, methyl ester, (3R,5S,6E)- (9CI, ACI); 7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-ht-6-enoic acid methyl ester; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid methyl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 692.3±65.0 °C at 760 mmHg
• 分子式: C₂₃H₃₀FN₃O₆S
• 分子量: 495.564
• 闪点: 372.5±34.3 °C
• 精确质量: 495.183929
• PSA: 138.30000
• LogP: 1.01
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.576
• 储存条件: 室温，干燥密封

安全

• 海关编码: 2935009090

合成路线

上下游产品

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下游产品  3
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海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%