190595-65-4

• 常用中文名：依折麦布中间体
• 常用英文名：(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one
• CAS号：190595-65-4
• 分子式：C₃₁H₂₅F₂NO₃
• 分子量：497.532
• 发布时间：2018-12-28 10:32:09
• 更新时间：2026-07-01 06:05:13

名称

• 中文名: (3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮
• 英文名: (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one
• 中文别名: (3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮(依替米贝中间体); 依折麦布杂质80; 依泽替米贝中间体B; (3R,4S)-1-(4-氟苯)-3-[3-(4-氟苯-3-氧基丙基]-4-[4-(苯甲氧基)苯基],2-氮杂环丁酮; (3R,4S)-1-(4-氟苯基)-3(R)-［3-(4-氟苯基)-3(S)-羰基丙基］-4(S)-(4-卞氧苯基)-2-氮杂环丁酮; (3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂啶-2-酮; 依折麦布中间体ZTB-7; (3R,4S)-4-(4-(BENZYLOXY)PHENYL)-1-(4-FLUOROPHENYL)-3-(3-(4-FLUOROPHENYL)-3-OXOPROPYL)AZETIDIN-2-ONE(3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮; 苄基依折麦布酮; 依泽替米贝杂质17; (3R,4S)-1-(4-氟苯基)-3-[3-氧代-3-(4 氟苯基)丙基]-4-(4-苄氧苯基)-2-氮杂环丁酮; 2-氮杂环丁烷酮, 1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]-4-[4-(苯基甲氧基)苯基]-, (3R,4S); (3R,4S)-1-(4-氟苯基)-3-[3-氧代-3-(4 氟苯基)丙基]-4-(4-苄氧苯基)-2-氮杂环丁酮/依泽替米贝中间体; (3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮依替米贝中间体; (3R,4S)-4-(4-(苄氧基)苯基)-1-(4-氟苯基)-3-(3-(4-氟苯基)-3-氧丙基)氮杂环丁烷-2-酮; 依泽替米贝中间体1; 依折麦布杂质17; (3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基); 1-(4氟苯基)-3-[3-氧代-3-(4氟苯基)丙基]-4-(4苄氧苯基)-2-氮杂环丁酮; 依折麦布中间体7; 胆固醇吸收抑制剂中间体2; 依折麦布中间体8
• 英文别名: Ezetimibe Impuriry 17; (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-benzyloxyphenyl)-2-azetidinone; Ezetimibe Intermediate-K; (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-2-azetidinone; 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-[4-(phenylMethoxy)phenyl]-, (3R,4S); E6:synthesis of trans-1-(4-fluorophenyl)-3-[3-oxo-3-(4-fluorophenyl)propyl; trans-1-(4-fluorophenyl)-3(R)-(3-oxo-3-(4-fluorophenyl)propyl)-4(S)-(4-benzyloxyphenyl)-2-azetidinone; EzetiMibe interdiate; Cholesterol absorption inhibitor 1; 3-oxopropyl); Ezetimibe intermediate 1; Acetylchloride,2-[5-(trifluoromethyl)phenoxy]; 1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one; Ezetimibe Impurity 17; (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin; ZTB-7; (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one190-4; EZ-ETK; 4-(4-(Benzyloxy); ETMB-06; Benzaldehyde,4-methoxy-8-(phenylmethoxy); (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one; (3R,4S)-4-[4- (benzyloxy) phenyl ]-1-(4- fluorophenyl) -3-[3-(4- fluorophenyl) -3- oxopropyl] azetidine -2- one; cholesterol-absorption inhibitor Intermediate 2; (3R, 4S) -4- [4- (benzyloxy) phenyl] -1- (4-fluorophenyl) -3- [3- (4-fluorophenyl) -3-oxopropyl] azacyclobutane-2-one; (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one, min; (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-f; (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-o; (3R,4S)-4-((4-benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-2-azetidinone; 3-(3-(4-fluorophenyl); 3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopr

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 706.8±60.0 °C at 760 mmHg
• 分子式: C₃₁H₂₅F₂NO₃
• 分子量: 497.532
• 闪点: 381.3±32.9 °C
• 精确质量: 497.180237
• PSA: 46.61000
• LogP: 6.10
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.610
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933790090

合成路线

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163380-20-9 191330-56-0

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%