247237-43-0

• 常用中文名：5-氯-2-[(4-乙氧基-4-氧代丁基)(4-甲基苯磺酰基)氨基]苯甲酸甲酯
• 常用英文名：methyl 5-chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate
• CAS号：247237-43-0
• 分子式：C₂₁H₂₄ClNO₆S
• 分子量：453.93600
• 发布时间：2019-01-10 11:37:44
• 更新时间：2026-08-06 08:49:57

名称

• 中文名: 5-氯-2-[(4-乙氧基-4-氧代丁基)(4-甲基苯磺酰基)氨基]苯甲酸甲酯
• 英文名: methyl 5-chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate
• 中文别名: 托伐普坦03; 托伐普坦杂质22; 托伐普坦杂质 2;5-氯-2-[(4-乙氧基-4-氧代丁基)(4-甲基苯磺酰基)氨基]苯甲酸甲酯
• 英文别名: 5-Chloro-2-[(3-ethoxycarbonyl-propyl)-(toluene-4-sulfonyl)-amino]-benzoic acid methyl ester; methyl 5-chloro-2-(N-(4-ethoxy-4-oxobutyl)-4-methylphenylsulfonamido)benzoate; 5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester; methyl 5-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate; Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate; Benzoic acid, 5-chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester; N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo [b]azine-1-carbonyl)-3-methylphenyl)-2-methyl-N-(2-methylbenzoyl)benzamide; Poly(ethylene glycol) Standd; Tolvaptan Impurity 22; I06-1507

物化性质

• 密度: 1.3
• 分子式: C₂₁H₂₄ClNO₆S
• 分子量: 453.93600
• 精确质量: 453.10100
• PSA: 98.36000
• LogP: 5.05440

合成路线

2969-81-5 247237-38-3 ~92% 247237-43-0

文献：Kondo, Kazumi; Ogawa, Hidenori; Yamashita, Hiroshi; Miyamoto, Hisashi; Tanaka, Michinori; Nakaya, Kenji; Kitano, Kazuyoshi; Yamamura, Yoshitaka; Nakamura, Shigeki; Onogawa, Toshiyuki; Mori, Toyoki; Tominaga, Michiaki Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1743 - 1754

5202-89-1 ~% 247237-43-0

文献：HETERO RESEARCH FOUNDATION; Reddy, Bandi Parthasaradhi; Reddy, Kura Rathnakar; Reddy, Dasari Muralidhara; Reddy, Maruthi Janakiram; Krishna, Bandi Vamsi Patent: US2013/190490 A1, 2013 ;

2516-95-2 ~% 247237-43-0

文献：HETERO RESEARCH FOUNDATION; Reddy, Bandi Parthasaradhi; Reddy, Kura Rathnakar; Reddy, Dasari Muralidhara; Reddy, Maruthi Janakiram; Krishna, Bandi Vamsi Patent: US2013/190490 A1, 2013 ;

51282-49-6 ~% 247237-43-0

文献：HETERO RESEARCH FOUNDATION; Reddy, Bandi Parthasaradhi; Reddy, Kura Rathnakar; Reddy, Dasari Muralidhara; Reddy, Maruthi Janakiram; Krishna, Bandi Vamsi Patent: US2013/190490 A1, 2013 ;

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