137982-91-3

• 常用中文名：7-氯-1,2,3,4-四氢-1-(2-甲基-4-硝基苯甲酰基)-5H-1-苯并氮杂卓-5-酮
• 常用英文名：7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
• CAS号：137982-91-3
• 分子式：C₁₈H₁₅ClN₂O₄
• 分子量：358.776
• 发布时间：2018-12-04 11:42:31
• 更新时间：2026-07-16 22:48:19

名称

• 中文名: 7-氯-1,2,3,4-四氢-1-(2-甲基-4-硝基苯甲酰基)-5H-1-苯并氮杂卓-5-酮
• 英文名: 7-chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-2H-1-benzazepin-5-one
• 中文别名: 氯-1,2,3,4-四氢-1-(2-甲基-4-硝基 苯甲酰基)-5H-1-苯并氮杂卓-5-酮; 托伐普坦杂质12; 7-氯-1-(2-甲基-4-硝基苯甲酰基)-3,4-二氢-1H-苯并[B]氮杂卓-5(2H)-酮; 托伐普坦09; 7-氯-1-(2-甲基-4-硝基苄基)-1,2,3,4-四氢-5H-苯并[B]氮杂卓-5-酮
• 英文别名: 7-chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-2H-1-benzazin-5-one; 5H-1-Benzazin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl); 7-chloro-1-(2-methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydrobenzo[b]azepin-5-one; 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazin-5-one; 7-chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine; 1H-benzo[b]azine; 7-Chloro-5-oxo-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzazine; 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one; Tovaptan impurity 32; 7-chloro-1 -(2-methyl-4-nitrobenzoyl)-3, 4-dihydro-1h-benzo [b] azine-5 (2H) -ketone; Tovaptan impurity 12; 7-chloro-1-(2-methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azin-5-one; 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1; 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; Tolvaptan Impurity 12; 7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3-dihydro-1H-benzo[b]azin-5-yl 2-methylbenzoate; 7-chloro-1-(2-Methyl-4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azin-5(2H)-one; Tolvaptan InterMediates; Tolvaptan Impurity 1; 7-Chloro-1,2,3,4-Tetrahydro-1-(2-Methyl-4-Nitrobenzoyl)-5H-1-Benzazine-5-One; 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazin-5-one CAS; 7- chloro -1,2,3,4- tetrahydro -1-(2- methyl -4- nitrobenzoyl) -5H-1- benzoazine -5- one

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 573.3±50.0 °C at 760 mmHg
• 分子式: C₁₈H₁₅ClN₂O₄
• 分子量: 358.776
• 闪点: 300.5±30.1 °C
• 精确质量: 358.072021
• PSA: 83.20000
• LogP: 3.74
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.635
• 储存条件: 室温，密闭，干燥

安全

• 海关编码: 2933990090

合成路线

30459-70-2 160129-45-3 ~32% 137982-91-3

文献：Kondo, Kazumi; Ogawa, Hidenori; Yamashita, Hiroshi; Miyamoto, Hisashi; Tanaka, Michinori; Nakaya, Kenji; Kitano, Kazuyoshi; Yamamura, Yoshitaka; Nakamura, Shigeki; Onogawa, Toshiyuki; Mori, Toyoki; Tominaga, Michiaki Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1743 - 1754

5202-89-1 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

2516-95-2 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

1975-51-5 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

51282-49-6 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

247237-38-3 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

193686-76-9 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

247237-43-0 ~% 137982-91-3

文献：Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754

上下游产品

上游产品  9
30459-70-2 160129-45-3 5202-89-1 2516-95-2
1975-51-5 51282-49-6 247237-38-3 193686-76-9
247237-43-0
下游产品  3
137977-97-0 137973-76-3 150683-30-0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%