中文名 | 1,4-二羟基-8-氟-4-羰基喹啉-3-羧酸乙酯 |
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英文名 | ethyl 1,4-dihydro-8-fluoro-4-oxoquinoline-3-carboxylate |
中文别名 |
8-氟-4-氧代-1,4-二氢喹啉-3-羧酸乙酯
1,4-二氢-8-氟-4-氧喹啉-3-羧酸乙酯 |
英文别名 |
MFCD00052242
8-FLUORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl 1,4-dihydro-8-fluoro-4-oxoquinoline ethyl 8-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate ETHYL 8-FLUORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE 8-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester BUTTPARK 18 9-67 ETHYL 8-FLUORO-4-HYDROXY-3-QUINOLINECARBOXYLATE ethyl-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate |
密度 | 1.172g/cm3 |
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沸点 | 166.1ºC at 760 mmHg |
熔点 | 217-219°C |
分子式 | C12H10FNO3 |
分子量 | 235.21100 |
闪点 | 53.7ºC |
精确质量 | 235.06400 |
PSA | 59.16000 |
LogP | 1.84390 |
折射率 | 1.498 |
储存条件 | 2-8°C,干燥密封 |
分子结构 | 1、 摩尔折射率:57.08 2、 摩尔体积(m3/mol):178.4 3、 等张比容(90.2K):462.8 4、 表面张力(dyne/cm):45.3 5、 极化率(10-24cm3):22.62 |
计算化学 | 1、 疏水参数计算参考值(XlogP):-3.2 2、 氢键供体数量:3 3、 氢键受体数量:4 4、 可旋转化学键数量:3 5、 拓扑分子极性表面积(TPSA):92 6、 重原子数量:11 7、 表面电荷:0 8、 复杂度:151 9、 同位素原子数量:0 10、 确定原子立构中心数量:1 11、 不确定原子立构中心数量:0 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:0 14、 共价键单元数量:1 |
更多 | 1. 性状:。 2. 密度(g/mL,25/4℃):未确定 3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(ºC):未确定 5. 沸点(ºC,常压):未确定 6. 沸点(ºC,5.2kPa):未确定 7. 折射率:未确定 8. 闪点(ºC):未确定 9. 比旋光度(º):未确定 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(kPa,25ºC):未确定 12. 饱和蒸气压(kPa,60ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:。 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 71083-06-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 217 - 219 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H10FNO3 Molecular Weight: 235 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, fluorine, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 71083-06-2 unlisted. LD50/LC50: Not available. Carcinogenicity: Ethyl 8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 71083-06-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 71083-06-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 71083-06-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
危害码 (欧洲) | Xi |
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风险声明 (欧洲) | R36/37/38 |
安全声明 (欧洲) | S26-S36/37/39 |
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