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56238-63-2生产厂家

56238-63-2价格

相关CAS号：
2172205-74-0 2648914-63-8
2228590-87-0 2171747-79-6
2172083-45-1 2649062-85-9
2649058-46-6 2172043-14-8
2171480-98-9 2171875-27-5

56238-63-2

56238-63-2结构式
56238-63-2结构式

化源商城直购

中文名 头孢呋辛钠
英文名 Cefuroxime Sodium Salt
中文别名 呋肟霉素钠
(6R,7R)-7-[2-呋喃基(甲氧亚氨基)乙酰氨基]-3-氨基甲酰氧甲基-8-氧代-5-硫杂-1-氮杂二环[4.2.0]辛-2-烯-2-甲酸钠
头孢呋辛钠 >855UG/MG
头孢呋辛钠盐
原料药头孢呋辛钠
原料头孢呋辛钠
头孢呋辛钠(药典标准品)
头孢呋新钠
Cefuroxime sodium试剂
头孢呋辛钠 56-2
化合物:Cefuroxime sodium (Cefuroxime sodium salt)
头孢呋辛钠CEFUROXIME SODIUM SALT
头孢呋辛酯杂质D钠盐
头孢呋辛钠(标准品)
头孢呋辛钠无菌
Cefuroxime Sodium 头孢呋辛钠
头孢呋肟钠
头孢呋辛酯杂质D钠
Cefuroxime sodium 头孢呋辛钠(无菌)
头孢呋辛钠 标准品
西力欣
头孢呋辛钠 头孢粉
头孢呋辛钠原料
化合物：Cefuroxime sodium (Cefuroxime sodium salt)
头孢呋辛纳
头孢呋辛钠盐标准品
头孢呋辛钠,10 MM DMSO 溶液
头孢呋辛钠及中间体
(6R,7R)-3-((氨基甲酰氧基)甲基)-7-((Z)-2-(呋喃-2-基)-2-(甲氧基亚氨基)乙酰氨基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛烷-2-烯-2-羧酸钠
无菌头孢呋辛钠
头孢呋辛钠无菌原料
呋辛钠
Cefuroxime Sodium for Injection 注射用头孢呋辛钠
英文别名 CefuroxiMe sodiuM salt CefuroxiMe sodiuM salt
CEFUROXIME SODIUM/ CEFUROXIME
Sodium [(6R)-[6a,7b(Z)]]-3-[[(aminocbonyl)oxy]methyl]-7-[2-furyl(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylate
Cefuroxime Sodium Salt Standd
cefuroime sodium sterile
(6R)-3-[(Cbamoyloxy)methyl]-7α-[[2-furanyl[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid sodium salt
Curoxim
Cefam
Spectrazole
7β-[[(Z)-2-(2-Furyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[(cbamoyloxy)methyl]cham-3-ene-4-cboxylic acid sodium salt
Cefroxine
Ultroxim
EINECS 260-073-1
Sterile cefuroxiMe sodiuM (2 bottles)
Cefuroxime (sodium)
Zinacef
Cefumax
CefuroximeSodiumSal
CEFUROXIME SODIUM SALT
ethyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-,monosodiumsalt,(6r-(
3-(cbamoyloxymethyl)-7-[[2-(2-furanyl)-2-methoxyimino-1-oxoethyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylate
Biociclin
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, 3-[[(aminocbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]
Zinace
Cefuroxime Sodium(sterile)
Cefuroxime Sodium
MFCD00079036
640
Cefuroxime Axetil Impurity D Sodium Salt
Biofurex
Medoxim
sodiumcefuroxime
sodium [6r-[6a,7b(z)]]-3-[[(aminocbonyl)oxy]methyl]-7-[2-furyl(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylate
zinacef
Anaptivan
Duxima
Gibicef
Cefurin
Top quality Cefuroxime Sodium
Cefoprim
Kesint
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1)
Cefurex
Ipacef
sodium (6R,7R)-3-((cbamoyloxy)methyl)
(6R,7R)-3-[[(Aminocbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid Sodium Salt
Cefuroxime sodium CRS
Novocef
Spectrazol
CefuroxiMe SodiuM sterile API
Lampsporin
sodium (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Cefuroxime sodium //BP
CEFUROXIME NA
Bioxima
sodium [6R-[6alpha,7beta(Z)]]-3-[[(aminocbonyl)oxy]methyl]-7-[2-furyl(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylate
CefuroxiMe sod
Curocef
CEFUROXIME SODIUM SALT hot-selling
Cefuroxime Sodium Salt (Cefuroxime Axetil Impurity D Sodium Salt)
7-beta(z)))-6-alph
5-Thia-1-azabicyclo4.2.0oct-2-ene-2-cboxylic acid, 3-(aminocbonyl)oxymethyl-7-(2Z)-2-furanyl(methoxyimino)acetylamino-8-oxo-, monosodium salt, (6R,7R)
Sodium (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-(2-furyl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SODIUM CEFUROXIME
描述 Cefuroxime钠是一种肠内或口服的第二代头孢类抗生素。
相关类别
熔点 240-245°C(dec)
分子式 C16H15N4NaO8S
分子量 446.367
精确质量 446.050842
PSA 201.89000
外观性状 白色结晶固体
储存条件

密封、在2 ºC -8 ºC下保存

稳定性

如果遵照规格使用和储存则不会分解，未有已知危险反应

计算化学

1、 疏水参数计算参考值（XlogP）：

2、 氢键供体数量：2

3、 氢键受体数量：9

4、 可旋转化学键数量：8

5、 互变异构体数量：4

6、 拓扑分子极性表面积（TPSA）：177

7、 重原子数量：30

8、 表面电荷：0

9、 复杂度：804

10、同位素原子数量：0

11、确定原子立构中心数量：2

12、不确定原子立构中心数量：0

13、确定化学键立构中心数量：1

14、不确定化学键立构中心数量：0

15、共价键单元数量：2

更多

1. 性状：未确定

2. 密度（g/mL,15ºC）：未确定

3. 相对蒸汽密度（g/mL,空气=1）： 未确定

4. 熔点（ºC）：240-245

5. 沸点（ºC）：未确定

6. 沸点（ºC，2mmHg）：未确定

7. 折射率：未确定

8. 闪点（°C）：未确定

9. 比旋光度（ºC）：未确定

10. 自燃点或引燃温度（ºC）： 未确定

11. 蒸气压（kPa,25ºC）：未确定

12. 饱和蒸气压（kPa,60ºC）：未确定

13. 燃烧热（KJ/mol）：未确定

14. 临界温度（ºC）：未确定

15. 临界压力（KPa）：未确定

16. 油水（辛醇/水）分配系数的对数值：未确定

17. 爆炸上限（%,V/V）：未确定

18. 爆炸下限（%,V/V）：未确定

19. 溶解性：未确定

生态学数据:

对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统，若无政府许可，勿将材料排入周围环境。

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI0330000
CHEMICAL NAME :
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2- furanyl(methoxyimino)acetyl)amino)-8-oxo-, monosodium salt, (6R-(6-alpha,7-beta(Z)))-
CAS REGISTRY NUMBER :
56238-63-2
LAST UPDATED :
199707
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C16-H15-N4-O8-S.Na
MOLECULAR WEIGHT :
446.40
WISWESSER LINE NOTATION :
T46 ANV ES GUTJ G1OVZ HVO CMVYUNO1&- BT5OJ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes
REFERENCE :
NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 27(Suppl 6),124,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - hypermotility, diarrhea
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 13,1,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 13,1,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 13,349,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,261,1982 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
43200 mg/kg
SEX/DURATION :
female 16-21 day(s) after conception lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 13,1,1979

符号 GHS07
GHS07
信号词 Warning
危害声明 H317
警示性声明 P280
危害码 (欧洲) Xn: Harmful;
风险声明 (欧洲) R42/43
安全声明 (欧洲) S22-S36/37-S45
危险品运输编码 NONH for all modes of transport
WGK德国 2
RTECS号 XI0330000
海关编码 2941905990
海关编码 2941905990
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