81839-27-2

• 常用中文名：α-Fluoromethyl-L-histidine dihydrochloride
• 常用英文名：α-Fluoromethyl-L-histidine dihydrochloride
• CAS号：81839-27-2
• 分子式：C₇H₁₂Cl₂FN₃O₂
• 分子量：260.094
• 发布时间：2021-01-10 09:28:59
• 更新时间：2025-09-13 09:48:52
• (S)-alpha-Fluoromethylhistidine HCl is a potent irreversible histidine decarboxylase (HDC) inhibitor and glutathione S-transferase inhibitor. a-FMH was demonstrated to be an effective inhibitor of GST at micromolar concentration, suggesting that off-target effects of a-FMH may limit physiological drug metabolism and elimination by GST-dependent mechanisms.

名称

• 英文名: α-(Fluoromethyl)-L-histidine dihydrochloride
• 英文别名: L-Histidine, α-(fluoromethyl)-, hydrochloride (1:2); α-(Fluoromethyl)-L-histidine dihydrochloride

物化性质

• 沸点: 503.2±0.0 °C at 760 mmHg
• 分子式: C₇H₁₂Cl₂FN₃O₂
• 分子量: 260.094
• 闪点: 258.1±0.0 °C
• 精确质量: 259.029053
• 蒸汽压: 0.0±0.0 mmHg at 25°C