81839-27-2
81839-27-2 structure
- Name: α-Fluoromethyl-L-histidine dihydrochloride
- Chemical Name: α-(Fluoromethyl)-L-histidine dihydrochloride
- CAS Number: 81839-27-2
- Molecular Formula: C7H12Cl2FN3O2
- Molecular Weight: 260.094
- Create Date: 2021-01-10 09:28:59
- Modify Date: 2025-09-13 09:48:52
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(S)-alpha-Fluoromethylhistidine HCl is a potent irreversible histidine decarboxylase (HDC) inhibitor and glutathione S-transferase inhibitor. a-FMH was demonstrated to be an effective inhibitor of GST at micromolar concentration, suggesting that off-target effects of a-FMH may limit physiological drug metabolism and elimination by GST-dependent mechanisms.
| Name | α-(Fluoromethyl)-L-histidine dihydrochloride |
|---|---|
| Synonyms |
L-Histidine, α-(fluoromethyl)-, hydrochloride (1:2)
α-(Fluoromethyl)-L-histidine dihydrochloride |
| Boiling Point | 503.2±0.0 °C at 760 mmHg |
|---|---|
| Molecular Formula | C7H12Cl2FN3O2 |
| Molecular Weight | 260.094 |
| Flash Point | 258.1±0.0 °C |
| Exact Mass | 259.029053 |
| Vapour Pressure | 0.0±0.0 mmHg at 25°C |