118081-34-8

• 常用中文名：头孢布坦
• 常用英文名：ceftibuten dihydrate
• CAS号：118081-34-8
• 分子式：C₁₅H₁₈N₄O₈S₂
• 分子量：446.455
• 相关类别： 原料药 抗生素类药物 头孢菌素类药
• 发布时间：2018-08-30 12:41:20
• 更新时间：2026-07-19 19:30:10
• Ceftibuten二水合物是第三代头孢类抗生素。

名称

• 中文名: 头孢布烯二水合物
• 英文名: ceftibuten dihydrate
• 中文别名: (+)-(6R,7R)-7-[2-(2-氨基-1,3-噻唑-4-基)-4-羧基-2-丁烯酰胺]]-8-氧-5-硫-1-氮双环[4.2.0]辛-2-烯-2-羧酸二水物; 头孢布烯(头孢布坦); 头孢布坦
• 英文别名: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylicacid, 7-[[2-(2-amino-4-thiazolyl)-4-cboxy-1-oxo-2-butenyl]amino]-8-oxo-,dihydrate, [6R-[6a,7b(Z)]]- (9CI); Sch-39720; (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-Yl)-4-Cboxybut-2-Enoylamino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Cboxylic Acid Dihydrate; Cedax; Seftem; Chalosporins cloth temple; Ceftibuten dehydrate; [6R-[6α,7β(Z)]]-7-[[2-(2-Amino-4-thiazolyl)-4-cboxy-1-oxo-2-(butenyl-13C3)]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid; (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-4-cboxybut-2-enamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid dihydrate; [6R-[6α,7β(Z)]]-7-[[2-(2-Amino-4-thiazolyl)-4-cboxy-1-oxo-2-butenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid Dihydrate; Sch-39720 dihydrate; Ceftibuten Dihydrate; S 7C3; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-, (6R,7R)-, hydrate (1:2); (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsäuredihydrat; Ceftibuten dihydrate, 10 mM in DMSO; Ceftibuten dihydrateQ: What is Ceftibuten dihydrate Q: What is the CAS Number of Ceftibuten dihydrate Q: What is the storage condition of Ceftibuten dihydrate Q: What e the applications of Ceftibuten dihydrate; Ceftibuten dihydrate Powder Standd; (+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-cboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid dihydrate; Ceftibuten Hydrate; (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,dihydrate; Ceftibuten dihydrate //BP; Ceftibuten 2-hydrate; CEDAX DIHYDRATE;SCH-39720 DIHYDRATE; Seftem (tn); Cedax-13C3; Cedax (tn); (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-4-carboxy-2-butenoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate; Chalosporin 7432-S-13C3; Ceftibuten (jp15); Cetb; D02121; Cedax dihydrate; Cefobuxene dihydrate

物化性质

• 沸点: 966.4ºC at 760mmHg
• 熔点: >180ºC (dec.)
• 分子式: C₁₅H₁₈N₄O₈S₂
• 分子量: 446.455
• 闪点: 538.3ºC
• 精确质量: 446.056610
• PSA: 234.92000
• LogP: 0.73320
• 外观性状: 淡黄色固体
• 蒸汽压: 0mmHg at 25°C
• 储存条件: -20°C Freezer

生物活性

• 描述: Ceftibuten二水合物是第三代头孢类抗生素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Wise R, et al. Ceftibuten--in-vitro activity against respiratory pathogens, beta-lactamase stability and mechanism of action. J Antimicrob Chemother, 1990. 26(2): p. 209-213.

安全

• 危害码 (欧洲): Xn