124199-90-2

• 常用中文名：(D-PHE6,LEU-NHET13,DES-MET14)-BOMBESIN (6-14)
• 常用英文名：(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) trifluoroacetate salt
• CAS号：124199-90-2
• 分子式：C₄₉H₆₉N₁₃O₉
• 分子量：984.154
• 相关类别： 信号通路 G 蛋白偶联受体/G 蛋白 Bombesin Receptor
• 发布时间：2018-12-31 14:09:52
• 更新时间：2026-07-27 03:14:59
• (D-Phe6,Leu-NHEt13,des-Met14)-Bombesin(6-14)是一种蛙皮素(BBN)拮抗剂,可用于癌症研究[1]。

名称

• 中文名: (D-PHE6,LEU-NHET13,DES-MET14)-BOMBESIN (6-14)
• 英文名: [D-Phe6,Leu-NHEt13,des-Met14]-Bombesin (6-14)
• 中文别名: D-PHE6,LEU-NHET13,DES-MET14]-蛙皮素; 蛙皮素(DPHE6, LEU-NHET13, DES-MET14)-BOMBESIN; D-苯丙氨酸6,亮氨酸-N-乙基酰胺13,去甲硫氨酸14]蛙皮素; [D-PHE, LEU-NHET13, DES-MET1]-蛙皮素
• 英文别名: (D-PHE6,LEU-NHET13,DES-MET14)-BOMBESIN; L-Leucinamide, D-phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl; D-PHE-GLN-TRP-ALA-VAL-GLY-HIS-LEU-NHET; D-Phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl-L-leucinamide; (D-Phe6,Leu-NHEt 13,des-Met14)-Bombesin trifluoroacetate salt; d-phe-gln-trp-ala-val-gly-his-leu-nhet; (D-Phe, Leu-NHEt13, des-Met1)-Bombesin; (D-Phe6,Leu-NHEt 13,des-Met14)-Bombesin trifluoroacetate salt H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt trifluoroacetate salt; H-D-PHE-GLN-TRP-ALA-VAL-GLY-HIS-LEU-NHET; h-d-phe-gln-trp-ala-val-gly-his-leu-nhet; (D-Phe,Leu-NHEt,des-Met)-Bombesin; D-Phe6; (d-phe6,leu-nhet13,des-met14)-bombesin (6-14)

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 1489.7±65.0 °C at 760 mmHg
• 分子式: C₄₉H₆₉N₁₃O₉
• 分子量: 984.154
• 闪点: 854.7±34.3 °C
• 精确质量: 983.534119
• PSA: 346.38000
• LogP: 1.67
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.595

生物活性

• 描述: (D-Phe6,Leu-NHEt13,des-Met14)-Bombesin(6-14)是一种蛙皮素(BBN)拮抗剂,可用于癌症研究[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> Bombesin Receptor
• 参考文献:

  [1]. Podstawka E, et al. Potential-dependent studies on the interaction between phenylalanine-substituted bombesin fragments and roughened Ag, Au, and Cu electrode surfaces. J Phys Chem B. 2010 Jan 21;114(2):1010-29.