94-19-9

• 常用中文名：球磺胺
• 常用英文名：sulfaethidole
• CAS号：94-19-9
• 分子式：C₁₀H₁₂N₄O₂S₂
• 分子量：284.35800
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-09-14 18:00:02
• 更新时间：2024-01-03 10:10:55

名称

• 中文名: 球磺胺
• 英文名: 4-amino-n-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
• 中文别名: 磺胺乙二唑
• 英文别名: globucin; aethazol; globuzid; etazol; Sulfaethidole; globucid; etazole; berlophen; sethadil; p-aminobenzenesulfonamide; ethazole; setd

物化性质

• 密度: 1.499g/cm3
• 沸点: 508.5ºC at 760 mmHg
• 分子式: C₁₀H₁₂N₄O₂S₂
• 分子量: 284.35800
• 闪点: 261.3ºC
• 精确质量: 284.04000
• PSA: 134.59000
• LogP: 3.21850
• 折射率: 1.666

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : WO9490000 CHEMICAL NAME : Sulfanilamide, N-(5-ethyl-1,3,4-thiadiazol-2-yl)- CAS REGISTRY NUMBER : 94-19-9 BEILSTEIN REFERENCE NO. : 0261474 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H12-N4-O2-S2 MOLECULAR WEIGHT : 284.38 WISWESSER LINE NOTATION : T5NN DSJ C2 EMSW&R DZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 211,367,1950 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1459 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 15,1597,1967

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2935009090

合成路线

1037-51-0 ~69% 94-19-9

文献：Ahad, Ali Md.; Zuohe, Song; Du-Cuny, Lei; Moses, Sylvestor A.; Zhou, Li Li; Zhang, Shuxing; Powis, Garth; Meuillet, Emmanuelle J.; Mash, Eugene A. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2046 - 2054

76170-72-4 ~72% 94-19-9

文献：Ganesh, Thota; Jiang, Jianxiong; Shashidharamurthy, Rangaiah; Dingledine, Ray ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 616 - 621

100-05-0 ~% 94-19-9

文献：Luk'yanov, A. V.; Onoprienko, V. S.; Borodina, K. S.; Zasosov, V. A.; Van'kovich, E. V.; et al. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 9 p. 640 - 644 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 9 p. 87 - 91

98-74-8 ~% 94-19-9

文献：Ganesh, Thota; Jiang, Jianxiong; Shashidharamurthy, Rangaiah; Dingledine, Ray ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 616 - 621

121-60-8 ~% 94-19-9

文献：Wojahn; Wuckel Archiv der Pharmazie (Weinheim, Germany), 1951 , vol. 284, p. 53,57

937-32-6 ~% 94-19-9

文献：Schering A.G. Patent: DE840544 , 1951 ; DRP/DRBP Org.Chem.

121-61-9 ~% 94-19-9

文献：Schering A.G. Patent: DE957841 , 1957 ;

上下游产品

上游产品  7
1037-51-0 76170-72-4 100-05-0 98-74-8
121-60-8 937-32-6 121-61-9
下游产品  0

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%