121058-85-3

• 常用中文名：5'-DMT-2'-TBDMS-AC-RC
• 常用英文名：5'-DMT-2'-TBDMS-Ac-rC
• CAS号：121058-85-3
• 分子式：C₃₈H₄₇N₃O₈Si
• 分子量：701.88100
• 相关类别： 信号通路 细胞周期/DNA损伤 DNA/RNA合成
• 发布时间：2018-11-24 19:02:24
• 更新时间：2026-06-30 22:58:49
• 5'-O-DMT-2'-O-TBDMS-Ac-rC是一种经过修饰的核苷,可用于合成DNA或RNA。

名称

• 中文名: N-(1-((2r,3r,4r,5r)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-3-((叔丁基二甲基甲硅烷基)氧基)-4-羟基四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)乙酰胺
• 英文名: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
• 中文别名: N-乙酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-O-[(叔丁基)二甲基硅烷基]胞苷; N-[1-[(2R,3R,4R,5R)-5-[[双(4-甲氧基苯基)(苯基)甲氧基]甲基]-3-[(叔丁基二甲基硅基)氧基]-4-羟基-2-四氢呋喃基]-2-氧代-1,2-二氢-4-嘧啶基]乙酰胺; 5'-DMT-2'-TBDMS-乙酰基胞苷; N-乙酰-5'-O-[二(4-甲氧基苯基)苯甲基]-2'-O-[(1,1-二甲基乙基)二甲基硅]-胞苷; N-乙酰基-5′-O-[双(4-甲氧基苯基)苯基甲基]-2′-O-(1,1-二甲基乙基)二甲基硅烷基]胞苷; N-乙酰基-5'-DMT-2'-TBDS-胞苷; 2'-DMTBS-5'-O-(4,4'-二甲氧基三苯甲基)-N4-乙酰基胞苷; N-(1-((2R,3R,4R,5R)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-3-((叔丁基二甲基硅烷基)氧基)-4-羟基四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)乙酰胺; DMT保护性胞苷(AC)
• 英文别名: 2'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]; 5'-O-DMTr-2'-O-TBDMS-rC(Ac); N-[1-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-2-tetrahydrofuryl]-2-oxo-1,2-dihydro-4-pyrimidinyl]acetamide; 5'-O-DMT-N-acetyl-2'-O-TBDMS-cytidine; N4-acetyl-2'-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)cytidine; N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl-N4-acetyl cytidine; N4-Acetyl-2'-O-TBDMS-5'-O-DMT-cytidine; 5-O-DMT-2-O-TBDMS-N-Ac-cytidin; 5-O-DMT-2-O-TBDMS-N-Ac-cytidine; N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine; 5’-O-DMT-2’-O-TBDMS-N4-Acetyl-Cytidine; 5'-O-DMT-2'-O-TBDMS-Ac-rC; TBS-Ac-rC; 2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidin; N-(1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-((tert-butyldiMethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyriMidin-4-yl)acetaMide; 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-cytidine; 5'-DMT-2'-O-TBDMS-N4-acetyl-cytidine; N4-Ac-2'-O-TBDMS-5'-O-DMT-C; N-(1-((2S,3S,4S,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(tert-butyldimethylsilyloxy)-4-hydroxy-tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine; N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-Cytidine; 2'-O-TBDMS-5'-O-DMT-N4-Ac cytidin; TBS-rC(Ac)

物化性质

• 密度: 1.19±0.1 g/cm3(Predicted)
• 分子式: C₃₈H₄₇N₃O₈Si
• 分子量: 701.88100
• 精确质量: 701.31300
• PSA: 133.86000
• LogP: 6.52580
• 储存条件: 2-8℃，干燥

生物活性

• 描述: 5'-O-DMT-2'-O-TBDMS-Ac-rC是一种经过修饰的核苷,可用于合成DNA或RNA。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成
  信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物

合成路线

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