898566-17-1

• 常用中文名：2-(4-氟苯基)-5-((5-碘-2-甲基苯基)甲基)噻吩
• 常用英文名：2-(4-Fluorophenyl)-5-[(5-iodo-2-Methylphenyl)methyl]thiophene
• CAS号：898566-17-1
• 分子式：C₁₈H₁₄FIS
• 分子量：408.272
• 相关类别： 医药中间体 原料药中间体
• 发布时间：2018-12-29 12:37:25
• 更新时间：2026-07-01 09:46:12
• 下载msds

名称

• 中文名: 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩
• 英文名: 2-(4-Fluorophenyl)-5-[(5-iodo-2-Methylphenyl)methyl]thiophene
• 中文别名: 卡格列净杂质D; 坎格列净 中间体5; T97干品; C-6碘化物; 2-(4-氟苯基)-5-(5-碘-2-甲基苄基)噻吩; 卡格列净中间体(C-6碘化物); 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩(坎格列净中间体); 2-(4-氟苯基)-5-(5-碘-2-甲基苯基)噻吩; 2-(4-氟苯基)-5-(2-甲基-5-碘苄基)噻吩; T97母液湿品; 卡格列净中间体,2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲 基]噻吩; 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]-硫苯; N,N-双(三氟甲基磺酰基)苯胺; 坎格列嗪杂质 D; 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩/898-1; 2-(2-甲基-5-溴苄基)-5-(4-氟苯)噻吩(坎格列净中间体); 卡那列净杂质52; 坎格列净的中间体; 2-(2-甲基-5-碘苯甲基)-5-(4-氟苯)噻吩; 2-[(5-碘-2-甲基苯基)甲基]-5-(4-氟苯基)-噻吩; 2-(4-氟苯)-5-(5-碘-2-甲基苄基)噻吩; 卡格列净中间体/碘噻吩/2-(2-甲基-5-碘苯甲基)-5-(4-氟苯)噻吩; 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩 卡格列净 中间体 KG-1; 2-(2-甲基-5-碘苄基)-5-(4-氟苯)噻吩; 卡那列净杂质D; 坎格列净中间体(898-1); 2-(4-氟苯基)-5-((5-碘-甲基苯基)甲基)噻吩; C-6碘化物/2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩; 坎格列净中间体; 2-(4-氟苯基)-5-((5-碘代-2-甲苯基)甲基)噻吩; T97(CCZ)P160601,2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩; (4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩; 卡格列净 中间体 KG-1.1; T97精品; 2-(4-氟苯基)-5-(5-碘-2-甲基苯甲基)噻吩; 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩(CG-201); 2-(4-氟苯基)-5-[(5-碘-2-甲基苯基)甲基]噻吩2-(4-FLUOROPHENYL)-5-[(5-IODO-2-METHYLPHENYL)METHYL]THIOPHENE
• 英文别名: Canagliflozin impurity-(2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene); 2-(4-Fluorophenyl)-5-(5-iodo-2-Methylbenzyl)thiophene; Canagliflozin Intermediate1; 2-(4-Fluorophenyl)-5-(5- iodo-methylphenyI) metl; Kangglinide Intermediate; Thiophene, 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]; Canagliflozin INT5; )-5-(5-iodo-2-methyL; Canagliflozin impurity DQ: What is Canagliflozin impurity D Q: What is the CAS Number of Canagliflozin impurity D Q: What is the storage condition of Canagliflozin impurity D; 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophen; 2-(5-iodo-2-methylbenzyl)-5-(4-fluoro-phenyl)thiophene; 5-(5-iodo-2-methylbenzyl); THI045; 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene ISO 9001：2015 REACH; 2-(4-Flurophenyl)-5-[(5-Iodo-2-methylphenyl] methyl] Thiophene; 2-(4-FLUOROPHENYL)-5-[(5-IODO-2-METHYLPHENYL)METHYL]THIOPHENE 898-1; 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene; Canagliflozin iMpurity D; 2-(5-iodo-2-methylbenzyl)-5-(4-fluoro-phenyl)thiophene; 2-(4-Fluoropheny1)-5-[(5-iodo-2 methylphenyl)methyl]thiophene; 2-(4-Fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene; Canagliflozin intermediates，2-(4-Fluorophenyl)-5-[(5-iodo-2- methylphenyl)methyl]thiophene; T5SJ B1R CI F1& ER DF; 2-((5-IODO-2-METHYLPHENYL)METHYL)-5-(4-FLUOROPHENYL)THIOPHENE; 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]; 2-(4-Fluorophenyl); 2-(4-Fluorophenyl)-5-(5-iodo-methylphenyl) methyl] thiophene

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 450.2±45.0 °C at 760 mmHg
• 熔点: 107-110°C
• 分子式: C₁₈H₁₄FIS
• 分子量: 408.272
• 闪点: 226.1±28.7 °C
• 精确质量: 407.984497
• PSA: 28.24000
• LogP: 7.20
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.643
• 储存条件: 室温，干燥

安全

• 符号: GHS05, GHS07
• 信号词: Danger
• 危害声明: H302-H318-H413
• 警示性声明: P280-P305 + P351 + P338
• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2934999090

合成路线

1030825-20-7 ~% 898566-17-1

文献：WO2009/35969 A1, ; Page/Page column 77 ; WO 2009/035969 A1

58861-48-6 108440-70-6 ~% 898566-17-1

文献：US2010/99883 A1, ; Page/Page column 40-41 ; US 20100099883 A1

上下游产品

上游产品  3
1030825-20-7 58861-48-6 108440-70-6
下游产品  1
842133-18-0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%