CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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VB2625000
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CAS REGISTRY NUMBER :
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1446-17-9
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LAST UPDATED :
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199201
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C18-H26-Cl-N3.H3-O4-P
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MOLECULAR WEIGHT :
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417.92
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WISWESSER LINE NOTATION :
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T66 BNJ EMY1&3N2&2 IG &P-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human
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DOSE/DURATION :
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43 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - acute pulmonary edema
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REFERENCE :
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JFSCAS Journal of Forensic Sciences. (American Soc. for Testing and Materials, 1916 Race St., Philadelphia, PA 19103) V.1- 1956- Volume(issue)/page/year: 5,201,1965
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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2740 mg/kg/39W
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TOXIC EFFECTS :
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Behavioral - muscle weakness
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REFERENCE :
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ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50; V.70-99, 1960-75. For publisher information, see APLMAS. Volume(issue)/page/year: 93,209,1972
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - child
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DOSE/DURATION :
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38 mg/kg
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TOXIC EFFECTS :
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Cardiac - other changes Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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PEDIAU Pediatrics. (American Academy of Pediatrics, P.O. Box 1034, Evanston, IL 60204) V.1- 1948- Volume(issue)/page/year: 27,95,1961 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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2660 mg/kg
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SEX/DURATION :
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female 2-39 week(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Effects on Newborn - other neonatal measures or effects Reproductive - Effects on Newborn - other postnatal measures or effects
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REFERENCE :
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AROTAA Archives of Otolaryngology. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-52, 1925-50; V.72- 1960- Volume(issue)/page/year: 80,407,1964
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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455 mg/kg
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SEX/DURATION :
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female 1-13 week(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - abortion
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REFERENCE :
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AROTAA Archives of Otolaryngology. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-52, 1925-50; V.72- 1960- Volume(issue)/page/year: 80,407,1964
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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420 mg/kg
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SEX/DURATION :
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female 1-6 week(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - musculoskeletal system
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REFERENCE :
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AROTAA Archives of Otolaryngology. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-52, 1925-50; V.72- 1960- Volume(issue)/page/year: 80,407,1964
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intramuscular
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DOSE :
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25 mg/kg
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SEX/DURATION :
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female 18 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - abortion
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REFERENCE :
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CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 31,173,1985
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