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13115-71-4生产厂家

13115-71-4价格

13115-71-4

13115-71-4结构式
13115-71-4结构式

化源商城直购

中文名 甘氨酰-L-谷氨酰胺一水合物
英文名 Glycyl-L-glutamine monohydrate
中文别名 甘氨酰-L-谷氨酰胺单水合物
甘氨酰-L-谷氨酰胺单水合物.甘氨酰-L-谷氨酰胺.甘氨酰谷氨酰胺.N-甘氨酰-L-谷氨酰胺.甘氨酰-L-谷氨
L-甘-谷二肽,甘氨酰-L-谷氨酰胺一水合物
L-甘-谷二肽
甘氨酰-L-谷氨酰胺
甘氨酰-L-谷氨酰胺
甘氨酰谷氨酰胺
甘氨酰-L-谷氨酰胺一水和物
英文别名 H-Gly-Gln-OH
Gly-l-Gln
(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoic acid
(S)-2-(2-Aminoacetylamino)-4-carbamoylbutyric acid
MFCD00077124
L-Glutamine, glycyl-
(2S)-5-Amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
ZV2YVQMV1Z &&L or S Form
(S)-5-Amino-2-(2-aminoacetamido)-5-oxopentanoic acid
Glycyl-L-glutamine
描述 Glycyl-glutamine (Glycyl-L-glutamine),是 β-endorphin 的酶裂解产品,是 β-内啡肽(1-31) 的内源拮抗剂。Glycyl-glutamine (Glycyl-L-glutamine) 是一种比谷氨酰胺 (Gln) 稳定的活性神经肽。
相关类别
体外研究 甘氨酰谷氨酰胺(Glycyl-L-glutamine,Glycyl-L-glutamine)是一种活性稳定的谷氨酰胺神经肽。甘氨酰谷氨酰胺(Glycyl-L-glutamine)作为细胞培养的生长因子,在高压灭菌和储存过程中均优于游离谷氨酰胺(Gln)[2]。
体内研究 甘氨酸谷氨酰胺(Glycyl-L-glutamine)(0.3,0.6,1.0和10.0nm)可剂量依赖性抑制戊巴比妥麻醉大鼠β端(1-31)诱导的低血压[1]。
参考文献

[1]. Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8

[2]. Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8.

密度 1.4±0.1 g/cm3
沸点 643.1±55.0 °C at 760 mmHg
熔点 194°C
分子式 C7H13N3O4
分子量 203.196
闪点 342.7±31.5 °C
精确质量 203.090607
PSA 144.74000
LogP -2.50
外观性状 白色晶体或结晶粉末
蒸汽压 0.0±4.1 mmHg at 25°C
折射率 1.538
储存条件 2-8°C
水溶解性 154 g/L (20 ºC)
分子结构

1、 摩尔折射率:46.72

2、 摩尔体积(m3/mol):149.4

3、 等张比容(90.2K):425.9

4、 表面张力(dyne/cm):65.9

5、 极化率(10-24cm3):18.52

计算化学

1、 疏水参数计算参考值(XlogP):-4.6

2、 氢键供体数量:4

3、 氢键受体数量:5

4、 可旋转化学键数量:6

5、 互变异构体数量:4

6、 拓扑分子极性表面积(TPSA):136

7、 重原子数量:14

8、 表面电荷:0

9、 复杂度:241

10、 同位素原子数量:0

11、 确定原子立构中心数量: 1

12、 不确定原子立构中心数量:0

13、 确定化学键立构中心数量:0

14、 不确定化学键立构中心数量:0

15、 共价键单元数量:1

更多

1. 性状:未确定

2. 密度(g/mL, 25 ℃ ):未确定

3. 相对蒸汽密度(g/mL,空气=1):未确定

4. 熔点(ºC):194

5. 沸点(ºC,常压):未确定

6. 沸点(ºC,0.1mmHg):未确定

7. 折射率:未确定

8. 闪点(ºC):未确定

9. 比旋光度(º,C=10,2N HCl):-6.5

10. 自燃点或引燃温度(ºC):未确定

11. 蒸气压(20ºC):未确定

12. 饱和蒸气压(kPa,60ºC):未确定

13. 燃烧热(KJ/mol):未确定

14. 临界温度(ºC):未确定

15. 临界压力(KPa):未确定

16. 油水(辛醇/水)分配系数的对数值:未确定

17. 爆炸上限(%,V/V):未确定

18. 爆炸下限(%,V/V):未确定

19. 溶解性:溶于水

Name: Glycyl-L-glutamine monohydrate 99% Material Safety Data Sheet
Synonym: Glutamine (L)-, glycyl
CAS: 13115-71-4
Section 1 - Chemical Product MSDS Name:Glycyl-L-glutamine monohydrate 99% Material Safety Data Sheet
Synonym:Glutamine (L)-, glycyl

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
13115-71-4 Glycyl-L-glutamine monohydrate 99 unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 13115-71-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: > 194 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >160 deg C
Solubility in water: 154 g/l (20 c)
Specific Gravity/Density: Not available.
Molecular Formula: C7H13N3O4.H2O
Molecular Weight: 221.22

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 13115-71-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Glycyl-L-glutamine monohydrate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 13115-71-4: 0
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 13115-71-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 13115-71-4 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
危害码 (欧洲) Xi:Irritant;
风险声明 (欧洲) R36/37/38
安全声明 (欧洲) S23-S24/25-S37/39-S26
WGK德国 -
海关编码 2924199090
上游产品  1

下游产品  0

海关编码 2924199090
中文概述 2924199090. 其他无环酰胺(包括无环氨基甲酸酯)(包括其衍生物及盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 包装
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%