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56281-36-8

56281-36-8结构式

常用中文名：毛替垂尼
常用英文名：2,4,6,8-Nonatetraenamide,N-ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (2E,4E,6E,8E)-
CAS号：56281-36-8
分子式：C₂₃H₃₁NO₂
分子量：353.49800
发布时间：2018-06-14 19:12:08
更新时间：2024-01-03 16:51:06

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中文名	毛替垂尼
英文名	motretinide
中文别名	莫维A胺
英文别名	N-ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenamide Tasmaderm 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethylamide (2E,4E,6E,8E)-N-Ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetrenamide 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetraensaeure-(N-ethyl)amid

密度	0.996g/cm3
沸点	560.3ºC at 760mmHg
分子式	C₂₃H₃₁NO₂
分子量	353.49800
闪点	292.7ºC
精确质量	353.23500
PSA	38.33000
LogP	5.60940
折射率	1.55

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RA8439000

CHEMICAL NAME :: 2,4,6,8-Nonatetraenamide, 3,7-dimethyl-N-ethyl-9-(4-methoxy-2,3,6-trimethylphen yl)-, (all-E)-

CAS REGISTRY NUMBER :: 56281-36-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H31-N-O2

MOLECULAR WEIGHT :: 353.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2478 mg/kg/2W-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 350 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988