453-11-2

453-11-2结构式

常用中文名：1-氯-3-氟-2-丙醇
常用英文名：2-Propanol,1-chloro-3-fluoro-
CAS号：453-11-2
分子式：C₃H₆ClFO
分子量：112.53100
相关类别：化学农药原药杀虫剂杀鼠剂
发布时间：2018-03-18 08:00:00
更新时间：2024-02-01 16:12:43
高毒、速效氟醇类杀鼠剂。主要用于野外灭鼠，尤其适用于草原牧区。能通过皮肤吸收，可经消化系统、呼吸系统或皮肤接触致鼠中毒死亡。使用含量0.6%，用于住宅、仓库、轮船等灭鼠时，将毒饵投入于鼠洞内（旁）或鼠经常活动的地方，每间房间投放4堆，每堆5～10g，田间灭鼠时每洞10g，投药后24h可见死鼠，2～4d出现高峰，4d后控制鼠患。

化源商城直购

中文名	1-氯-3-氟-2-丙醇
英文名	1-chloro-3-fluoroisopropanol
英文别名	1-chloro-3-fluoro-propan-2-ol 1-chloro-3-fluoro-2-propano chloro-1 fluoro-3 propanol-2 2-propanol,1-chloro-3-fluoro MFCD00045284 1-fluoro-3-chloro-isopropanol 1-Chlor-3-fluor-propan-2-ol 1-Chloro-3-fluoro-2-propanol

密度	1.3
沸点	158.1ºC at 760mmHg
分子式	C₃H₆ClFO
分子量	112.53100
闪点	49.4ºC
精确质量	112.00900
PSA	20.23000
LogP	0.55560
蒸汽压	0.951mmHg at 25°C
折射率	1.438
储存条件	密封保存，放置于通风、干燥地方，避免于其他氧化物接触。
稳定性	按规格使用和贮存，不会发生分解，避免与氧化物接触
分子结构	1、摩尔折射率：22.45 2、摩尔体积（m³/mol）：92.7 3、等张比容（90.2K）：213.5 4、表面张力（dyne/cm）：28.0 5、极化率（10 ^-24cm ³）：8.90
计算化学	1、疏水参数计算参考值（XlogP）：0.5 2、氢键供体数量：1 3、氢键受体数量：2 4、可旋转化学键数量：2 5、互变异构体数量： 6、拓扑分子极性表面积（TPSA）：20.2 7、重原子数量：6 8、表面电荷：0 9、复杂度：34 10、同位素原子数量：0 11、确定原子立构中心数量：0 12、不确定原子立构中心数量：1 13、确定化学键立构中心数量：0 14、不确定化学键立构中心数量：0 15、共价键单元数量：1
更多	1. 性状：无色或微黄色液体 2. 密度（g/ m³,25/4℃）：1.3 3. 相对蒸汽密度（g/cm³,空气=1）：未确定 4. 熔点（ºC）：未确定 5. 沸点（ºC,常压）：153 6. 沸点（ºC,5.2kPa）：未确定 7. 折射率：1.438 8. 闪点（ºC）：153-156 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,25ºC）：未确定 12. 饱和蒸气压（kPa,60ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：溶于水

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: 1-Chloro-3-ﬂuoroisopropanol
Synonyms:

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

H331:Toxic if inhaled
H302:Harmful if swallowed
H312:Harmful in contact with skin
H226:Flammable liquid and vapour
Keep away from heat/sparks/open ﬂames/hot surfaces. No smoking
P210:
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P280:Wear protective gloves/protective clothing/eye protection/face protection
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower
P405:Store locked up

Section3. Composition/information on ingredients.
Ingredient name:1-Chloro-3-ﬂuoroisopropanol
CAS number:453-11-2

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C3H6ClFO
Molecular weight: 112.5

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen chloride, hydrogen ﬂuoride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN1992Class: 3Packing group: III
Proper shipping name: FLAMMABLE LIQUIDS, TOXIC, N.O.S. (1-Chloro-3-ﬂuoroisopropanol)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

毒理学数据:

急性毒性：小鼠经静脉：320 mg/kg，除致死剂量外无详细说明；

生态学数据:

该物质对环境可能有危害，对水体应给予特别注意。

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA9000000

CHEMICAL NAME :: 2-Propanol, 1-chloro-3-fluoro-

CAS REGISTRY NUMBER :: 453-11-2

BEILSTEIN REFERENCE NO. :: 1732051

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C3-H6-Cl-F-O

MOLECULAR WEIGHT :: 112.54

WISWESSER LINE NOTATION :: G1YQ1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00320

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R10;R20/21/22
安全声明 (欧洲)	S23-S36/37
危险品运输编码	UN 2929
包装等级	III

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