18361-45-0

• 常用中文名：Leucomycin A5
• 常用英文名：Leucomycin A5
• CAS号：18361-45-0
• 分子式：C₃₉H₆₅NO₁₄
• 分子量：771.93200
• 发布时间：2017-09-27 00:03:41
• 更新时间：2024-01-02 11:33:58
• Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 μg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 μg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 μg/ml, respectively) and S. faecalis (MIC = 0.8 μg/ml).

名称

• 英文名: [2,3'-Bi-1H-indole]-2',3-diol
• 英文别名: leuco-indirubin; leucomycin A5

物化性质

• 密度: 1.22g/cm3
• 沸点: 871.4ºC at 760 mmHg
• 分子式: C₃₉H₆₅NO₁₄
• 分子量: 771.93200
• 闪点: 480.8ºC
• 精确质量: 771.44100
• PSA: 199.98000
• LogP: 2.19660
• 蒸汽压: 1.86E-35mmHg at 25°C
• 折射率: 1.543
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OH4726170 CHEMICAL NAME : Leucomycin V, 4(sup B)-butanoate CAS REGISTRY NUMBER : 18361-45-0 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C39-H65-N-O14 MOLECULAR WEIGHT : 772.05 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309