中文名 | 重酒石酸去甲肾上腺素 |
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英文名 | L-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol bitartrate |
中文别名 | (R)-4-(2-氨基-1-羟基乙基)-1,2-苯二酚重酒石酸盐一水合物 |
英文别名 |
Norepinephrine Bitartrate
MFCD00150449 4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol 2,3-dihydroxysuccinate (1:1) 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, 2,3-dihydroxybutanedioate (1:1) (salt) EINECS 211-268-5 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol 2,3-dihydroxybutanedioate (1:1) 4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol 2,3-dihydroxysuccinate (1:1) |
沸点 | 100-106°C |
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熔点 | 100-106ºC |
分子式 | C12H17NO9 |
分子量 | 319.265 |
精确质量 | 319.090332 |
PSA | 201.77000 |
外观性状 | 白色或类白色晶体 |
储存条件 | 室温,干燥 |
Section 1. Chemical Product and Company Identification Norepinerphrine Bitartrate, Monohydrate Catalog N3233, N3550 Common Name/ Number(s). Trade Name CAS#69815-49-2 or 108341-18-0;
51-40-1[anhydrous] Manufacturer Commercial Name(s) Norepinerphrine Bitartrate, Monohydrate Section 3. Hazards Identification Potential Acute Health Effects Very hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation. Severe over-exposure can result in death. Potential Chronic HealthCARCINOGENIC EFFECTS: Not available. EffectsMUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to the nervous system, heart, cardiovascular system, Smooth muscle. Repeated or prolonged exposure to the substance can produce target organs damage. Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs. Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Flash PointsNot available. Flammable LimitsNot available. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Products of Combustion Fire Hazards in Presence of Slightly flammable to flammable in presence of heat. Various Substances Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available. of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available. Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks onNot available. Fire Hazards Special Remarks on Explosion Not available. Hazards Norepinerphrine Bitartrate, Monohydrate Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7. Handling and Storage PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not breathe dust. Keep away from incompatibles such as oxidizing agents, acids, alkalis. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Air Sensitive Sensitive to light. Store in light-resistant containers. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid.OdorNot available. TasteNot available. Molecular Weight337.3 g/mole Not available. Color Not available. pH (1% soln/water) Boiling PointNot available. 100°C (212°F) Melting Point Critical TemperatureNot available. Specific GravityNot available. Vapor PressureNot applicable. Vapor DensityNot available. VolatilityNot available. Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Ionicity (in Water)Not available. Dispersion PropertiesNot available. SolubilityNot available. Norepinerphrine Bitartrate, Monohydrate Section 10. Stability and Reactivity Data The product is stable. Stability Instability TemperatureNot available. Excess heat, incompatible materials, light, air. Conditions of Instability Reactive with oxidizing agents, acids, alkalis. Incompatibility with various substances CorrosivityNot available. Special Remarks onAir and light sensitive. Reactivity Special Remarks onNot available. Corrosivity PolymerizationWill not occur. Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. Toxicity to AnimalsLD50: Not available. LC50: Not available. Chronic Effects on Humans May cause damage to the following organs: the nervous system, heart, cardiovascular system, Smooth muscle. Other Toxic Effects onVery hazardous in case of ingestion. HumansSlightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation. Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherAcute Potential Health Effects: Toxic Effects on HumansSkin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: Dust may cause respiratory tract irritation with coughing, wheezing, shortness of breath Ingestion: May be fatal if swallowed. May cause nausea, vomiting, sweating, photophobia. May affect behavior/central nervous system (headache, anxiety, dizziness, weakness, mental/mood changes, convulsions, excitement), respiration (respiratory difficulty, respiratory stimulation), cardiovascular system/heart (palpitations, hypertension, cardiac arrhythmias, fast or slow heartbeat). Medical Conditions Aggravated by Exposure: Mesenteric or peripheral thrombosis (blood clots); hypertension; dehydration; thyroid problems (especially hyperthyroidism); (taking monoamine oxidase inhibitors (MAO) or antidepressants of the triptyline or imipramine types; during Cyclopropane or halthane anesthesia. Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the ProductsThe product itself and its products of degradation are not toxic. of Biodegradation Special Remarks on theNot available. Products of Biodegradation Norepinerphrine Bitartrate, Monohydrate Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14. Transport Information DOT ClassificationCLASS 6.1: Poisonous material. : Toxic solid, organic (norepinephrine bitartrate monohydrate) UNNA: 2811 PG: II Identification Not available. Special Provisions for Transport DOT (Pictograms) Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. Proposition 65 Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsEINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances. Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non-Domestic Substances List (NDSL) China: Not isted on National Inventory. Japan: Not isted on National Inventory (ENCS). Korea: Not listed on National Inventory (KECI). Philippines: Not listed on National Inventory (PICCS). Australia: Not isted on AICS. WHMIS (Canada) CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). Other Classifications DSCL (EEC)R28- Very toxic if swallowed.S28- After contact with skin, wash immediately with plenty of [***] S36/37- Wear suitable protective clothing and gloves. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Health Hazard HMIS (U.S.A.)3 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 3 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) Norepinerphrine Bitartrate, Monohydrate DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. SECTION 16 - ADDITIONAL INFORMATION N/A |
危害码 (欧洲) | T |
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风险声明 (欧洲) | 26/27/28 |
安全声明 (欧洲) | 45 |
危险品运输编码 | UN 2811 6.1/PG 3 |
WGK德国 | 3 |
RTECS号 | DN6750000 |
海关编码 | 2922210000 |
海关编码 | 2922210000 |
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