154226-60-5

• 常用中文名：CLASTO-LACTACYSTIN BETA-LACTONE,20S PROTEASOME抑制剂
• 常用英文名：Omuralide
• CAS号：154226-60-5
• 分子式：C₁₀H₁₅NO₄
• 分子量：213.230
• 发布时间：2017-07-14 19:53:55
• 更新时间：2026-07-03 13:25:41
• A potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity)..

名称

• 中文名: CLASTO-LACTACYSTIN BETA-LACTONE,20S PROTEASOME抑制剂
• 英文名: CLASTO-LACTACYSTIN β-LACTONE
• 中文别名: clasto-Lactacystin β-lactone试剂
• 英文别名: Clasto-lactacystin (OMuralide); LACTACYSTIN, CLASTO-, BETA-LACTONE; (3S,4S,7R,8S)-8-Hydroxy-3-isopropyl-7-methyl-2-oxa-5-azaspiro[3.4]octane-1,6-dione; Tri-p-tolylstibine; Clasto-Lactacystin Beta-lactone; 1-(1-Hydroxy-2-methylpropyl)-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; Stibine,tri-p-tolyl; OMURALIDE; clasto-Lactacystin beta-lactone, 20S proteasome inhibitor; 5,6,7,12,6'-pentamethoxy-2-methyl-berbam-1'-ene; BETA-CLASTOLACTACYSTIN; clasto-lactacystin β-lactone; (1R,4R,5S)-1-[(1S)-1-Hydroxy-2-Methylpropyl]-4-Methyl-6-oxa-2-azabicyclo[3.2.0]htane-3,7-dione; 6-Oxa-2-azabicyclo[3.2.0]htane-3,7-dione, 1-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-, (1R,4R,5S); CLASTO-LACTACYSTIN BETA-LACTONE; Tri-p-tolylantimony; 1R-[1S-1HYDROXY-2-METHYLPROPYL]-4R-METHYL-6-OXA-2-AZABICYCLO[3.2.0]HTANE-3,7-DIONE

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 462.9±45.0 °C at 760 mmHg
• 分子式: C₁₀H₁₅NO₄
• 分子量: 213.230
• 闪点: 233.7±28.7 °C
• 精确质量: 213.100113
• PSA: 75.63000
• LogP: -1.40
• 蒸汽压: 0.0±2.6 mmHg at 25°C
• 折射率: 1.534

安全

• 符号: GHS06
• 信号词: Danger
• 危害声明: H301-H315-H319-H335
• 警示性声明: P261-P301 + P310-P305 + P351 + P338
• 危险品运输编码: UN 2811 6.1 / PGIII

合成路线

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