Omuralide

更新时间：2025-08-25 10:16:34

Omuralide结构式	常用名	Omuralide	英文名	Omuralide
	CAS号	154226-60-5	分子量	213.230
	密度	1.3±0.1 g/cm3	沸点	462.9±45.0 °C at 760 mmHg
	分子式	C₁₀H₁₅NO₄	熔点	N/A
	MSDS	美版	闪点	233.7±28.7 °C
	符号	GHS06	信号词	Danger

Omuralide用途

A potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity)..

英文名	CLASTO-LACTACYSTIN β-LACTONE
英文别名	更多

密度	1.3±0.1 g/cm3
沸点	462.9±45.0 °C at 760 mmHg
分子式	C₁₀H₁₅NO₄
分子量	213.230
闪点	233.7±28.7 °C
精确质量	213.100113
PSA	75.63000
LogP	-1.40
InChIKey	FWPWHHUJACGNMZ-BSZUBZAZSA-N
SMILES	CC(C)C(O)C12NC(=O)C(C)C1OC2=O
蒸汽压	0.0±2.6 mmHg at 25°C
折射率	1.534

符号	GHS06
信号词	Danger
危害声明	H301-H315-H319-H335
警示性声明	P261-P301 + P310-P305 + P351 + P338
危险品运输编码	UN 2811 6.1 / PGIII

Omuralide上游产品 4
CAS号145451-97-4 (3R,4s,5r)-4-羟基... CAS号212772-65-1 (1R,4R,5S)-1-((... CAS号167773-32-2 (2R,3R,4R,1'S)-... CAS号87421-19-0 (2R)-2-Amino-3-...
Omuralide下游产品 0

Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines.

Virus Res. 142(1-2) , 68-77, (2009)

Proteasome inhibitor, which inhibits NF-kappaB activation, has been reported to activate c-Jun N-terminal kinase (JNK)-c-Jun pathway. In this study, we investigated the effects of proteasome inhibitor...

Turnover of StAR protein: roles for the proteasome and mitochondrial proteases.

Mol. Cell. Endocrinol. 265-266 , 51-8, (2007)

Steroidogenic acute regulatory protein (StAR) is a mitochondrial protein essential for massive synthesis of steroid hormones in the adrenal and the gonads. Our studies suggest that once synthesized on...

Targeting of a chlamydial protease impedes intracellular bacterial growth.

PLoS Pathog. 7(9) , e1002283, (2011)

Chlamydiae are obligate intracellular bacteria that propagate in a cytosolic vacuole. Recent work has shown that growth of Chlamydia induces the fragmentation of the Golgi apparatus (GA) into ministac...

实验名称：Inhibition of clasto-lactacystin binding to beta2 subunit of 20S proteasome in human ...
来源：ChEMBL
靶标：Proteasome subunit beta type-2
External Id：CHEMBL1007984

实验名称：Inhibition of clasto-lactacystin binding to beta5 subunit of 20S proteasome in human ...
来源：ChEMBL
靶标：Proteasome subunit beta type-5
External Id：CHEMBL1007983

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