120595-80-4

• 常用中文名：P-乙酰氨基苯-B-D-葡萄糖酸钠盐
• 常用英文名：acetaminophen glucuronide sodium salt
• CAS号：120595-80-4
• 分子式：C₁₄H₁₆NNaO₈
• 分子量：349.27
• 相关类别： 生物化工 糖类化合物 单糖
• 发布时间：2019-01-26 10:22:53
• 更新时间：2026-07-15 10:24:30
• Acetaminophen glucuronide 是一种安全有效的解热镇痛剂。Acetaminophen glucuronide对肝脏和肾脏具有潜在毒性。

名称

• 中文名: P-乙酰氨基苯-B-D-葡萄糖酸钠盐
• 英文名: p-Acetamidophenyl β-D-glucuronide sodium salt
• 中文别名: P-对乙酰氨基苯BETA-D-葡萄糖苷酸钠盐; p-对乙酰氨基苯Beta-D-葡萄糖苷酸钠盐; 扑热息痛葡萄糖醛酸钠盐; 对乙酰氨基酚杂质17; (4-乙酰氨基苯基)- Β-D-葡糖苷酸钠盐; 对乙酰氨基酚杂质29; 对乙酰氨基酚葡萄糖醛酸钠盐; 对乙酰氨基酚O-Β-D-葡萄糖醛酸钠; 对乙酰氨基酚-O-Β-D-葡糖苷酸,钠盐; 4-乙酰氨基苯基β-D-葡萄糖醛酸钠盐; 4-乙酰氨基苯基-BETA-D-葡糖苷酸钠; (4-乙酰氨基苯基)-Β-D-葡糖苷酸钠盐; 对乙酰氨基酚-O-Β-D-葡糖苷酸钠盐; 4-乙酰氨基苯Β-D-葡萄糖酸钠盐; 扑热息痛葡糖苷酸钠盐; 对乙酰氨基酚杂质3
• 英文别名: Acetaminophen-O-beta-D-glucuronide, sodium salt; 4-Acetamidophenyl β-D-Glucuronide Sodium Salt; Acetaminophen O-β-D-glucuronide sodium salt; p-Acetamidophenyl β- D -glucuronide sodium salt; MFCD00153898; Acetaminophen glucuronide,Paracetamol glucuronide; Pacetamol-O-beta-D-glucuronide, p-Acetylaminophenol-O-beta-D-glucuronide, 4-Acetamidophenyl-O-beta-D-glucuronide; Sodium (2S,3S,4S,5R,6S)-6-(4-acetamidophenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-cboxylate; b-D-Glucopyranosiduronic acid,4-(acetylamino)phenyl, monosodium salt (9CI); 4-ACETAMIDOPHENYL B-D-GLUCURONIDE, SODIUM SALT; P-ACETAMIDOPHENYL BETA-D-GLUCURONIDE SODIUM SALT; 1-O-[4-(Acetylamino)phenyl]-β-D-glucopyranuronic acid; sodium 6-(4-acetamidophenoxy)-3,4,5-trihydroxy-2-oxanecboxylate; PACETAMOL GLUCURONIDE; Acetaminophen glucuronide Paracetamol glucuronide; PACETAMOL GLUCURONIDE SODIUM SALT; 4-(Acetylamino)phenyl β-D-glucuronide; ACETAMINOPHEN GLUCURONIDE SODIUM SALT; Pacetamol Impurity 2; 4-ACETAMIDOPHENYL BETA-D-GLUCURONIDE, SODIUM SALT; 4-Acetamidophenyl -D-Glucuronide, Sodium Salt; Pacetamol Impurity 17; Acetaminophen-O-β-D-glucuronide, sodium salt; P-ACETAMIDOPHENYL-B-D-GLUCURONIDE SODIUM SALT; 4-(Acetylamino)phenyl β-D-glucopyranosiduronic acid; P-acetamidophenyl B-D-glucuronide*sodium; Sodium 4-(acetylamino)phenyl beta-D-glucopyranosiduronate, Pacetamol glucuronide, sodium salt; p-Acetamidophenyl β-D-glucuronide sodium salt,Acetaminophen glucuronide, Pacetamol glucuronide; Acetaminophen-O-beta-D-glucuronide, sodium salt min; 4-acetamidophenol glucuronide; ACETAMINOPHEN GLUCURONIDE

物化性质

• 熔点: 232-233ºC (dec)
• 分子式: C₁₄H₁₆NNaO₈
• 分子量: 349.27
• 精确质量: 349.07700
• PSA: 148.38000
• 外观性状: 灰白色水晶般的固体
• 储存条件: −20°C

生物活性

• 描述: Acetaminophen glucuronide 是一种安全有效的解热镇痛剂。Acetaminophen glucuronide对肝脏和肾脏具有潜在毒性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. MazaleuskayaLL, et al. PharmGKB summary: pathways of acetaminophen metabolism at thetherapeutic versus toxic doses. Pharmacogenet Genomics. 2015 Aug;25(8):416-26.

安全

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xi: Irritant;
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3

合成路线

30824-21-6 ~84% 120595-80-4

文献：Hayes, John A.; Eccles, Kevin S.; Lawrence, Simon E.; Moynihan, Humphrey A. Carbohydrate Research, 2012 , vol. 349, p. 108 - 112

72692-06-9 ~% 120595-80-4

文献：Carbohydrate Research, , vol. 349, p. 108 - 112

92420-89-8 ~% 120595-80-4

文献：Carbohydrate Research, , vol. 349, p. 108 - 112

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