361-37-5

• 常用中文名：美西麦角
• 常用英文名：methysergide
• CAS号：361-37-5
• 分子式：C₂₁H₂₇N₃O₂
• 分子量：353.45800
• 发布时间：2018-09-27 09:39:45
• 更新时间：2024-01-03 19:30:29

名称

• 中文名: 美西麦角
• 英文名: methysergide
• 英文别名: Metisergide; Desernil; Deseril; Methysergid; Sansert; Metisergide [DCIT]; Desernyl; Deseryl; methsergide; Methysergidum; (6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide

物化性质

• 密度: 1.28g/cm3
• 沸点: 634.4ºC at 760mmHg
• 分子式: C₂₁H₂₇N₃O₂
• 分子量: 353.45800
• 闪点: 337.5ºC
• 精确质量: 353.21000
• PSA: 57.50000
• LogP: 2.26390
• 折射率: 1.658

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KE5300000 CHEMICAL NAME : Ergoline-8-beta-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimeth yl- CAS REGISTRY NUMBER : 361-37-5 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H27-N3-O2 MOLECULAR WEIGHT : 353.51 WISWESSER LINE NOTATION : T C6656 1A P GN LN CUTT&&J EVMY2&1Q G1 L1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 28 ug/kg TOXIC EFFECTS : Behavioral - anorexia (human) Behavioral - headache Gastrointestinal - nausea or vomiting REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,220,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 440 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963