302-40-9

• 常用中文名：胃复康
• 常用英文名：Benactyzine
• CAS号：302-40-9
• 分子式：C₂₀H₂₅NO₃
• 分子量：327.41700
• 相关类别： 原料药 抗应激药
• 发布时间：2018-03-22 08:00:00
• 更新时间：2024-01-13 01:14:51

名称

• 中文名: 贝那替嗪
• 英文名: 2-(diethylamino)ethyl 2-hydroxy-2,2-diphenylacetate
• 中文别名: 2-二乙基氨基乙基 2-羟基-2,2-二苯基乙酸酯; 胃复康
• 英文别名: Benzilsaeure-(2-diaethylamino-aethylester); Benzilic acid,2-(diethylamino)ethyl ester; Benzactyzine; Benactyzinum [INN-Latin]; Benactizina [Italian]; Diphenyl-glykolsaeure-<2-diaethylamino-aethylester>; Benactyzin; Benacticina [INN-Spanish]; 2-diethylaminoethyl benzilate; Diethylaminoethyl benzilate; BENACTYZINE; Benactizina [DCIT]

物化性质

• 密度: 1.115 g/cm3
• 沸点: 409.3ºC at 760 mmHg
• 熔点: 51ºC
• 分子式: C₂₀H₂₅NO₃
• 分子量: 327.41700
• 闪点: 201.4ºC
• 精确质量: 327.18300
• PSA: 49.77000
• LogP: 2.80750
• 折射率: 1.557
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DD2480000 CHEMICAL NAME : Benzilic acid, 2-(diethylamino)ethyl ester CAS REGISTRY NUMBER : 302-40-9 BEILSTEIN REFERENCE NO. : 2156821 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C20-H25-N-O3 MOLECULAR WEIGHT : 327.46 WISWESSER LINE NOTATION : QXR&R&VO2N2&2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Human DOSE/DURATION : 100 ug/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 159 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold MUTATION DATA TEST SYSTEM : Rodent - hamster DOSE/DURATION : 10 mg/kg REFERENCE : ACNSAX Activitas Nervosa Superior. (Avicenum, Malostranske nam. 28, Prague 1, Czechoslovakia) V.1- 1959- Volume(issue)/page/year: 17,253,1975

安全

• 危害码 (欧洲): T
• 风险声明 (欧洲): 23/24/25
• 安全声明 (欧洲): 36/37/39-45
• 海关编码: 2922509090

合成路线

869-24-9 ~% 302-40-9

文献：Journal of the American Chemical Society, , vol. 64, p. 431 Journal of the Chemical Society, , p. 59 Chemische Berichte, , vol. 71, p. 1651 Chem.Abstr., , p. 5078

869-24-9 5928-68-7 ~% 302-40-9

文献：Journal of the American Chemical Society, , vol. 64, p. 431 Journal of the Chemical Society, , p. 59 Chemische Berichte, , vol. 71, p. 1651 Chem.Abstr., , p. 5078

76-93-7 100-35-6 ~% 302-40-9

文献：Zhurnal Obshchei Khimii, , vol. 25, p. 2132,2134, 2136; engl. Ausg. S. 2091, 2092,2094

100-37-8 2902-98-9 ~% 302-40-9

文献：Collection of Czechoslovak Chemical Communications, , vol. 15, p. 541,549

100-37-8 52182-15-7 ~% 302-40-9

文献：US2394770 , ;

91431-81-1 ~% 302-40-9

文献：Pharmaceutical Chemistry Journal, , vol. 18, # 3 p. 161 - 164 Khimiko-Farmatsevticheskii Zhurnal, , vol. 18, # 3 p. 297 - 300

上下游产品

上游产品  7
869-24-9 5928-68-7 76-93-7 100-35-6
100-37-8 2902-98-9 52182-15-7
下游产品  3
3166-62-9 6699-38-3 6422-50-0

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%