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66547-10-2

66547-10-2结构式
66547-10-2结构式
  • 常用中文名:ANSAMITOCIN P-4
  • 常用英文名:ANSAMITOCIN P-4
  • CAS号:66547-10-2
  • 分子式:C33H45ClN2O9
  • 分子量:649.17100
  • 发布时间:2017-05-11 05:20:08
  • 更新时间:2024-01-17 18:32:47

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英文名 Maytansine, 3-de(2-(acetylmethylamino)-1-oxopropoxy)-3-(3-methyl-1-oxobutoxy)
英文别名 Tam 340
ansamitocin P-4
Maytansinol isovalerate
密度 1.28g/cm3
沸点 838.7ºC at 760 mmHg
分子式 C33H45ClN2O9
分子量 649.17100
闪点 461ºC
精确质量 648.28100
PSA 136.16000
LogP 5.10750
折射率 1.58
储存条件 库房通风低温干燥,与食品原料分开存放

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OQ2295000
CHEMICAL NAME :
Maytansine, 3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-, isovalerate (ester)
CAS REGISTRY NUMBER :
66547-10-2
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C33-H45-Cl-N2-O9
MOLECULAR WEIGHT :
649.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
625 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - mouse Ascites tumor
DOSE/DURATION :
4 ug/kg
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1707,1980