103980-44-5

• 常用中文名：盐酸头孢噻呋
• 常用英文名：Ceftiofur HCl
• CAS号：103980-44-5
• 分子式：C₁₉H₁₈ClN₅O₇S₃
• 分子量：560.023
• 相关类别： 原料药 抗生素类药物 头孢菌素类药
• 发布时间：2018-04-10 08:00:00
• 更新时间：2026-06-30 09:25:21
• Ceftiofur hydrochloride 是一种半合成抗生素,对针对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。

名称

• 中文名: 盐酸头孢噻呋
• 英文名: Ceftiofur Hydrochloride
• 中文别名: 头孢噻呋盐酸盐,10 MM DMSO 溶液; 头孢噻呋系列/盐酸头孢噻呋; (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸盐酸盐; (6R,7R)-7-((Z)-2-(2-氨基噻唑-4-基)-2-(甲氧基亚氨基)乙酰胺基)-3-((呋喃-2-羰基)硫基)甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸盐酸盐; Ceftiofur Hydrochloride 盐酸头孢噻呋; (6R,7R)-7-{[(2Z)-2-(2-氨基-4-噻唑基)-2-(甲氧亚氨基)乙酰基]氨基}-3-{[(2-呋喃甲酰基)硫代]甲基}-8-氧-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸 盐酸盐; 甲醇中盐酸头孢噻呋; 盐酸头孢噻呋(进口); 盐酸头孢噻呋(分普通粉和超微粉); 盐酸头孢噻呋(头孢噻呋); 盐酸头孢噻呋/103-5; 盐酸头孢噻呋(标准品); 头孢噻呋盐酸盐 标准品; 盐酸头孢替呋; 盐酸头孢噻呋(头孢噻呋盐酸盐)检测标准品; 头孢噻呋钠(口服级); 头孢替呋盐酸盐; 盐酸头孢噻呋杂质; 酸头孢噻; 盐酸头孢噻呋 Ceftiofur HCL; Ceftiofur hydrochloride 10mM * 1mL in DMSO试剂; 头孢噻呋盐酸盐; 盐酸噻呋钠; Ceftiofur hydrochloride 1000mg试剂; (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-3-甲酸盐酸盐; (6R,7R)-7-[2-(2-氨基噻唑-4-基)-(Z)-2-(甲基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-3-头孢烯-4-羧酸; 3-[(2-呋喃羰基)硫代]甲基]-7-[2-(2-氨基-4-噻唑基)-2-(甲氧基亚氨基乙酰胺基)-3-头孢烯-4-羧酸 盐酸盐; 盐酸头孢噻呋(兽用); 头孢噻呋类原料药
• 英文别名: Ceftiofur hydrochlor; Ceftiovir hydrochloride; (6r-(6alpha,7beta(z))-7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid hydrochloride; 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid hydrochloride; (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-cbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid; (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.]oct-2-ene-2-cboxylic acid hydrochloride; CEFTIOFUR HYDROCHLORIDE; Excenel hydrochloride; Ceftiofur Trimer Impurity 1; Excenel RTU; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-cboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcbonyl)thio)methyl)-8-oxo, monohydrochloride, (6R,7R); Ceftiofur hydrochloride //BP; N-(4-cyano-3-(trifluoroMethyl)phenyl)-3-(4-fluorobenzenesulfonyl)-2,2-diMethylpropanaMide; 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[[2-furanyl(oxo)methyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid; Cefotaxime hydrochloride 103-5; 103-5 Ceftiofur hydrochloride; 3-(((furan-2-carbonyl); U-67279A; (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid; C11065020 Ceftiofur hydrochloride; Ceftiofur hydrochlorideQ: What is Ceftiofur hydrochloride Q: What is the CAS Number of Ceftiofur hydrochloride Q: What is the storage condition of Ceftiofur hydrochloride; Ceftiofur Hydrochloride Non-sterile/Sterile; (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (1:1); Ceftiofur hydrochloride Impurities; Ceftiofur hydrochloride, 10 mM in DMSO; (6R,7R)-7-((Z)-2-(2-AMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-3-(((furan-2-carbonyl)thio)Methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid hydrochloride; U 64279A; Ceftiofur hydrochloride [103-5]; Unii-6822A; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, (6R,7R)-, hydrochloride (1:1); CEFTIOFUR HCL; (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, hydrochloride (1:1)

物化性质

• 沸点: 814.1ºC at 760 mmHg
• 熔点: >190°C (dec.)
• 分子式: C₁₉H₁₈ClN₅O₇S₃
• 分子量: 560.023
• 闪点: 446.1ºC
• 精确质量: 559.005676
• PSA: 256.26000
• LogP: 2.69300
• 外观性状: 灰白色固体
• 蒸汽压: 5.14E-28mmHg at 25°C
• 储存条件: -20°C Freezer

生物活性

• 描述: Ceftiofur hydrochloride 是一种半合成抗生素,对针对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点:

  bacterial[1]

• 参考文献:

  [1]. Fernández-Varón E, et al. Pharmacokinetics (PK), pharmacodynamics (PD), and PK-PD integration of ceftiofur after a single intravenous, subcutaneous and subcutaneous-LA administration in lactating goats. BMC Vet Res. 2016 Oct 13;12(1):232.

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2941905990

海关

海关编码	2941905990