104010-37-9

• 常用中文名：头孢噻呋钠
• 常用英文名：Ceftiofur sodium
• CAS号：104010-37-9
• 分子式：C₁₉H₁₆N₅NaO₇S₃
• 分子量：545.544
• 相关类别： 原料药 抗生素类药物 头孢菌素类药
• 发布时间：2018-06-30 06:06:23
• 更新时间：2024-01-02 11:29:03
• 属抗生素类药，用于治疗猪细菌性呼吸道感染

名称

• 中文名: 头孢噻呋钠
• 英文名: Ceftiofur sodium salt
• 中文别名: 头孢替呋(钠盐); (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸钠盐
• 英文别名: sodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Sodium ceftiofur; Ceftiofur sodium salt; Sodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; T46 ANV ES GUTJ HVQ CMVYUNO1&- ET5N CSJ BZ& G1SV- BT5OJ &&Na salt; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, sodium salt, (6R,7R)- (1:1); Ceftiofur monosodium salt; Ceftiofur sodium; Ceftiofur (sodium)

物化性质

• 密度: 1.81g/cm3
• 分子式: C₁₉H₁₆N₅NaO₇S₃
• 分子量: 545.544
• 精确质量: 545.010925
• PSA: 259.09000
• LogP: 0.55630
• 外观性状: 灰白色或淡黄色结晶粉末
• 储存条件: 室温，干燥

生物活性

• 描述: Ceftiofurna钠是第三代头孢菌素类抗生素,已批准用于兽医用途。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: Ceftiofur sodium Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Ceftiofur sodium CAS number:104010-37-9 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C19H16N5O7S3.Na Molecular weight:545.6 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XI0367360 CHEMICAL NAME : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl) (methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)th io)methyl)-8-oxo-, monosodium salt (6R-(6-alpha,7-beta(Z))- CAS REGISTRY NUMBER : 104010-37-9 LAST UPDATED : 199606 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H17-N5-O7-S3.Na MOLECULAR WEIGHT : 546.58 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 275 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 345,27,1995

安全

• 危害码 (欧洲): Xi
• 海关编码: 2941905990

海关

海关编码	2941905990