13636-18-5

• 常用中文名：芬迪烷盐酸盐
• 常用英文名：Fendiline Hydrochloride
• CAS号：13636-18-5
• 分子式：C₂₃H₂₆ClN
• 分子量：351.91200
• 相关类别： 信号通路 跨膜转运 钙通道
• 发布时间：2018-05-06 08:00:00
• 更新时间：2026-07-16 11:11:38
• Fendiline是非选择性的钙通道抑制剂。

名称

• 中文名: 芬迪烷盐酸盐
• 英文名: 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine,hydrochloride
• 中文别名: 盐酸芬他林,10 MM DMSO 溶液; 盐酸芬他林 Fendiline hydrochloride; 3,3-二苯基-N-(1-苯乙基)丙-1-胺 盐酸盐; 盐酸芬他林
• 英文别名: (3,3-diphenylpropyl)(1-phenylethyl)ammonium chloride; 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine hydrochloride; Fendiline (hydrochloride); n-(3,3-diphenylpropyl)-alpha-methyl-benzylaminhydrochloride; Sensit; Fendiline HCl; Ca2+ channels,Calcium Channel,Fendiline hydrochloride,Fendiline,Inhibitor,Ca channels,inhibit; difmecor; gamma-phenyl-n-(1-phenylethyl)-benzenepropanaminhydrochloride; n-(1-phenylethyl)-3,3-diphenylpropylaminehydrochloride; Fendil; FENDILINE HYDROCHLORIDE; Fendiline hydrochloride; N-[3,3-DIPHENYLPROPYL]-ALPHA-METHYLBENZYLAMINE HYDROCHLORIDE; N-(3,3-Diphenylpropyl)-α-methylbenzylamine; N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride; 3,3-Diphenyl-N-(1-phenylethyl)propan-1-amine hydrochloride; hk137; Fendiline hydrochloride, 10 mM in DMSO; gamma-phenyl-n-(1-phenylethyl)benzenepropanaminehydrochloride

物化性质

• 密度: 1.031g/cm3
• 沸点: 452.1ºC at 760mmHg
• 分子式: C₂₃H₂₆ClN
• 分子量: 351.91200
• 闪点: 207.9ºC
• 精确质量: 351.17500
• PSA: 12.03000
• LogP: 6.75230
• 外观性状: 粉末
• 蒸汽压: 2.3E-08mmHg at 25°C
• 储存条件: -20℃

生物活性

• 描述: Fendiline是非选择性的钙通道抑制剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钙通道
  研究领域 >> 心血管疾病

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DP4790000 CHEMICAL NAME : Benzylamine, N-(3,3-diphenylpropyl)-alpha-methyl-, hydrochloride CAS REGISTRY NUMBER : 13636-18-5 LAST UPDATED : 199601 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C23-H25-N.Cl-H MOLECULAR WEIGHT : 351.95 WISWESSER LINE NOTATION : 1YR&M2YR&R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 950 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 14500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): 36
• 危险品运输编码: NONH for all modes of transport
• RTECS号: DP4790000