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52600-53-0

52600-53-0结构式
52600-53-0结构式

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中文名 5-乙酰基-6-甲基-2-氧代-1,2-二羟基吡啶-3-甲腈
英文名 5-acetyl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
中文别名 5-乙酰-2-羟基-6-甲基烟碱
5-乙酰基-6-甲基-2-羟基吡啶-3-甲腈
英文别名 5-acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
5-acetyl-6-methyl-1,2-dihydro-2-oxo-3-pyridinecarbonitrile
5-Acetyl-2-hydroxy-6-methylnicotinonitrile
5-acetyl-2-hydroxy-6-methylpyridine-3-carbonitrile
5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile
3-cyano-5-acetyl-6-methylpyridin-2(1H)-one
5-acetyl-1,2-dihydro-6-methyl-2-oxonicotinonitrile
密度 1.25g/cm3
沸点 359.4ºC at 760mmHg
熔点 233-235ºC
分子式 C9H8N2O2
分子量 176.17200
精确质量 176.05900
PSA 73.98000
LogP 1.16988
折射率 1.546
储存条件 2-8°C, 密封, 干燥
Name: 5-Acetyl-6-methyl-2-oxo-1 2-dihydropyridine-3-carbonitrile 97% Material Safety Data Sheet
Synonym: 5-Acetyl-3-cyano-6-methyl-2-pyridon
CAS: 52600-53-0
Section 1 - Chemical Product MSDS Name:5-Acetyl-6-methyl-2-oxo-1 2-dihydropyridine-3-carbonitrile 97% Material Safety Data Sheet
Synonym:5-Acetyl-3-cyano-6-methyl-2-pyridon

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
52600-53-0 5-Acetyl-6-methyl-2-oxo-1,2-dihydropyr 97% unlisted
Hazard Symbols: XN
Risk Phrases: 20/21/22

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 52600-53-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: tan
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 226 - 228 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H8N2O2
Molecular Weight: 176

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Bases, oxidizing agents.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 52600-53-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.*
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
IMO
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
RID/ADR
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 52600-53-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 52600-53-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 52600-53-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
危害码 (欧洲) Xi
风险声明 (欧洲) R20/21/22
安全声明 (欧洲) S36/37
海关编码 2933399090

~45%

52600-53-0结构式

52600-53-0

文献:Abu-Shanab; Redhouse; Thompson; Wakefield Synthesis, 1995 , # 5 p. 557 - 560

~43%

52600-53-0结构式

52600-53-0

文献:Merrell Dow Pharmaceuticals Inc. Patent: US4568751 A1, 1986 ;

~92%

52600-53-0结构式

52600-53-0

文献:Mosti, Luisa; Schenone, Pietro; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1503 - 1509

~86%

52600-53-0结构式

52600-53-0

文献:Mosti, Luisa; Schenone, Pietro; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1503 - 1509

~%

52600-53-0结构式

52600-53-0

文献:Jones Jr.; Schnettler; Huber Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 511 - 518

~%

52600-53-0结构式

52600-53-0

详细
文献:Sterling Drug Inc. Patent: US4469699 A1, 1984 ;

~%

详细
文献:Sterling Drug Inc. Patent: US4469699 A1, 1984 ;

~%

52600-53-0结构式

52600-53-0

文献:Jones Jr.; Schnettler; Huber Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 511 - 518
海关编码 2933399090
中文概述 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%