1351692-92-6

1351692-92-6结构式

常用中文名：非布索坦酰基-β-D-葡糖醛酸
常用英文名：Febuxostat acyl glucuronide
CAS号：1351692-92-6
分子式：C₂₂H₂₄N₂O₉S
分子量：492.50
相关类别：信号通路代谢酶/蛋白酶黄嘌呤氧化酶
发布时间：2017-09-01 13:40:41
更新时间：2026-07-03 20:03:26
Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) 是 Febuxostat (HY-14268) 的代谢物。Febuxostat 是一种有效的、选择性的非嘌呤类黄嘌呤氧化酶 (XO) 抑制剂。

中文名	非布索坦酰基-β-D-葡糖醛酸
英文名	(2S,3S,4S,5R,6S)-6-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
中文别名	非布索坦酰基-Β-D-葡萄糖醛酸非布索坦酰基葡萄糖苷酸非布司他杂质89 非布索坦酰基葡糖醛酸非布司他杂质21 非布索坦酰基-BETA-D-葡糖苷酸非布索坦酰基-Β-D-葡萄糖苷酸化合物:Febuxostat Acyl Glucuronide 非布索坦酰基-Β-D-葡糖苷酸 FEBUXOSTAT ACYL-尾-D-GLUCURONIDE 化合物：Febuxostat Acyl Glucuronide 非布索坦酰基葡萄糖醛酸
英文别名	β-D-Glucopyranuronic acid, 1-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecboxylate] (2S,3S,4S,5R,6S)-6-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyl]oxy-3,4,5-trihydroxyoxane-2-cboxylic acid Febuxostat Acyl-\|A-D-glucuronide Febuxostat-acyl-beta-D-glucuronide min 2-[3-Cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecboxylate β-D-Glucopyranuronic Acid Febuxostat Acyl-β-D-glucuronide 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylate \|A-D-Glucopyranuronic Acid Febuxostat Impurity 2-(3-Cyano-4-isobutyloxyphenyl)-4-Methyl- 5-thiazolecboxylate β-D-Glucopyranuronic Acid 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylate \|A-D-Glucopyranuronic Acid

描述	Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) 是 Febuxostat (HY-14268) 的代谢物。Febuxostat 是一种有效的、选择性的非嘌呤类黄嘌呤氧化酶 (XO) 抑制剂。
相关类别	研究领域 >> 代谢疾病信号通路 >> 代谢酶/蛋白酶 >> 黄嘌呤氧化酶
参考文献	[1]. Bishoy Kamel, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475. [2]. Kamel B, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.