Febuxostat acyl glucuronide

Modify Date: 2024-08-16 12:36:59

Febuxostat acyl glucuronide Structure
Febuxostat acyl glucuronide structure
Common Name Febuxostat acyl glucuronide
CAS Number 1351692-92-6 Molecular Weight 492.50
Density N/A Boiling Point N/A
Molecular Formula C22H24N2O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Febuxostat acyl glucuronide


Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].

 Names

Name (2S,3S,4S,5R,6S)-6-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonym More Synonyms

 Febuxostat acyl glucuronide Biological Activity

Description Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].
Related Catalog
References

[1]. Bishoy Kamel, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.  

[2]. Kamel B, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.  

 Chemical & Physical Properties

Molecular Formula C22H24N2O9S
Molecular Weight 492.50
Exact Mass 492.12000
PSA 207.67000
LogP 1.07398

 Synonyms

Febuxostat Acyl-|A-D-glucuronide
2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylate |A-D-Glucopyranuronic Acid
2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylate |A-D-Glucopyranuronic Acid
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