113400-36-5

• 常用中文名：N-叔丁氧羰基-L-焦谷氨酸苄酯
• 常用英文名：Boc-L-Pyroglutamic acid benzyl ester
• CAS号：113400-36-5
• 分子式：C₁₇H₂₁NO₅
• 分子量：319.352
• 相关类别： 生物化工 氨基酸及其衍生物 谷氨酸类衍生物
• 发布时间：2018-12-17 11:26:42
• 更新时间：2026-07-01 12:16:09

名称

• 中文名: (S)-2-1-叔丁基 5-氧代吡咯烷-1,2-二羧酸苄酯
• 英文名: 2-O-benzyl 1-O-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
• 中文别名: N-BOC-L-焦谷氨酸苄酯; (S)-叔丁基 5-氧代吡咯烷-1,2-二羧酸苄酯; 叔丁氧羰基-焦谷氨酸苄酯; BOC-焦谷氨酸苄酯; 叔丁氧羰基-L-焦谷氨酸苄酯; N-BOC-L-焦谷氨酸 苄酯,BENZYL (S)-1-BOC-5-OXOPYRROLIDINE-2-CBOXYLATE; BOC-焦谷氨酯苄酯; 苄氧羰基-焦谷氨酸苄酯; N-叔丁氧羰基-L-焦谷氨酸苄酯,维帕他韦中间体; C4-叔丁氧羰基-L-焦谷氨酸苄酯; N-BOC-L-焦谷氨酸 苄酯; BOC-L-焦谷氨酸卞脂; BOC-L-焦谷氨酯苄酯
• 英文别名: benzyl 1-(t-butoxycarbonyl)pyroglutamate; 2-Benzyl 1-(2-methyl-2-propanyl) (2S)-5-oxo-1,2-pyrrolidinedicarboxylate; 2-benzyl 1-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicboxylat; 2-benzyl1-(tert-butyl)(S)-5-oxopyrrolidine-1,2-dicboxylate; 1,2-Pyrrolidinedicboxylic acid, 5-oxo-, 1-(1,1-diMethylethyl)2-(phenylMethyl) ester, (S); 2-benzyl 1-tert-butyl (2S)-5-oxo-1,2-pyrrolidinedicarboxylate; PYR294; (2S)-benzyl N-(tert-butyloxycarbonyl)-pyroglutamate; benzyl (2S)-N-tert-butoxycarbonyl-pyroglutamate; Boc-l-pyroglutamate benzyl ester; (S)-2-Benzyl 1-tert-butyl 5-oxopyrrolidine-1,2-dicarboxylate; phenylmethyl (S)-1-(1,1-dimethylethoxycarbonyl)-5-oxopyrrolidine-2-carboxylate; 2-Benzyl 1-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate; Boc-Pyr-Obzl; (2S)-benzyl N-(tert-butyloxycbonyl)-pyroglutamate; T-butoxycbonyl-l-pyroglutamic acid benzyl ester; 1,2-Pyrrolidinedicboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-(phenylmethyl) ester, (2S); Benzyl(S)-1-Boc-5-oxopyrrolidine-2-cboxylate; Boc-PyroglutaMic acid. Benzyl ester; (S)-2-Benzyl 1-tert-butyl 5-oxopyrrolidine-1,2-dicboxylate; BOC-L-PYROGLUTAMIC ACID BENZYL ESTER //BP; Benzyl (S)-1-Boc-5-oxopyrrolidine-2-cboxylate; (2R)-5-Oxo-1,2-pyrrolidinedicboxylic acid 1-(tert-butyl) 2-(phenylmethyl) ester; N-BOC-L-Pyroglutamic acid benzyl ester; Boc-Pyr-Obzl-OH; 2-benzyl 1-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicboxylate; Boc-L-Pyroglutamicacidbenzylester; (Tert-Butoxy)carbonyl Pyr-OBzl; N-tert-Butoxycbonyl-L-pyroglutamic acid Benzyl ester; BOC-L-PYROGLUTAMIC ACID BENZYL ESTER; 1,2-Pyrrolidinedicarboxylic acid,5-oxo-,1-(1,1-dimethylethyl)2-(phenylmethyl) ester,(S); 1-(1,1-Dimethylethyl) 2-(phenylmethyl) (2S)-5-oxo-1,2-pyrrolidinedicboxylate; 2-O-benzyl 1-O-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicboxylate; Boc-Pyr-OBzl

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 464.9±38.0 °C at 760 mmHg
• 分子式: C₁₇H₂₁NO₅
• 分子量: 319.352
• 闪点: 235.0±26.8 °C
• 精确质量: 319.141968
• PSA: 72.91000
• LogP: 1.37
• 外观性状: Powder | White
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.542
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933790090

合成路线

24424-99-5 94885-52-6 ~98% 113400-36-5

文献：Tetrahedron Letters, , vol. 43, # 19 p. 3499 - 3501

98-79-3 ~95% 113400-36-5

文献：EP1970377 A1, ; Page/Page column 55 ;

34619-03-9 94885-52-6 ~% 113400-36-5

文献：WO2006/24501 A1, ; Page/Page column 41 ; WO 2006/024501 A1

135347-23-8 ~38% 34989-82-7 113400-36-5

文献：Tetrahedron, , vol. 53, # 30 p. 10545 - 10554

100-39-0 ~% 113400-36-5

文献：Organic Letters, , vol. 6, # 9 p. 1469 - 1471

30924-93-7 ~% 113400-36-5

文献：Journal of Medicinal Chemistry, , vol. 41, # 15 p. 2819 - 2834

100-51-6 ~% 113400-36-5

文献：Journal of the American Chemical Society, , vol. 123, # 39 p. 9706 - 9707

100-44-7 ~% 113400-36-5

文献：Bioorganic and Medicinal Chemistry, , vol. 15, # 10 p. 3474 - 3488

上下游产品

上游产品  9
24424-99-5 94885-52-6 98-79-3 34619-03-9
135347-23-8 100-39-0 30924-93-7 100-51-6
100-44-7
下游产品  7
334769-80-1 91229-91-3 885618-31-5 53100-44-0
331949-31-6 863660-29-1 41324-66-7

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%