上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：盐酸奇霉素
纯度：98.0%
规格：1ml/200mg/1g/1g
联系人：阿拉丁

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联系电话：400-620-6333

苏州市森菲达化工有限公司
江苏省苏州市相城区
产品名：盐酸大观霉素
纯度：98.0%
规格：200kg
联系人：程经理

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联系电话：18796480002

湖北鑫红利化工有限公司
湖北省省直辖县级行政单位天门市
产品名：盐酸大观霉素
纯度：99.0%
规格：500g/1kg/25kg/200kg
联系人：魏女士

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联系电话：18871490254

上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：盐酸奇霉素
纯度：98.0%
规格：
联系人：小陈

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21736-83-4生产厂家

21736-83-4价格

21736-83-4

21736-83-4结构式

常用中文名：盐酸大观霉素
常用英文名：Spectinomycin dihydrochloride
CAS号：21736-83-4
分子式：C₁₄H₂₆Cl₂N₂O₇
分子量：405.271
相关类别：原料药抗生素类药物氨基糖苷类药
发布时间：2018-02-04 08:00:00
更新时间：2026-06-30 16:43:37
Spectinomycin双盐酸盐是不经肠道的抗生素,由壮观链霉菌制备而来。

化源商城直购

中文名	盐酸大观霉素
英文名	spectinomycin dihydrochloride
中文别名	大观霉素一水合二盐酸盐盐酸壮观霉素/奇霉素/奇放线菌素/放线壮观霉素奇放素菌素盐酸盐淋必治奇霉素/壮观霉素溶液(50MG/ML) 盐酸大观霉 Spectinomycin HCl 10mM * 1mL in DMSO试剂利泰霉素盐酸奇霉素壮观霉素,奇霉素,奇放线菌素盐酸大观霉素原料药 Spectinomycin dihydrochloride 纯粉五水 7 壮观霉素,奇霉素,奇放线菌素(盐酸大观霉素) (2R,4,5,6S,7S,8R,9S,9,10AS)-4A,7,9-三羟基-2-甲基-6,8-双(甲基氨基)十氢-4H-苯并[B]吡喃并[2,3-E][1,4]二氧杂环己烷基-4-酮二盐酸盐盐酸大观霉素无菌粉盐酸大观霉素(壮观) 壮观霉素二盐酸盐盐酸大观霉素/壮观霉素盐酸盐/奇放素菌素盐酸盐/淋必治大观霉素二盐酸盐盐酸大观霉素/壮观霉素/淋必治盐酸大观霉素林可霉素可溶性粉盐酸大观霉素(兽用) 化合物:Spectinomycin dihydrochloride 犬大观霉素前体盐酸大观霉素(医用) 化合物：Spectinomycin dihydrochloride 抗细菌中间体盐酸大观霉素/盐酸壮观霉素/医药
英文别名	U-18409AE Spectinomycin (50mg/ml) 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, [2R-(2a,4ab,5ab,6b,7b,8b,9a,9aa,10ab)]- (8CI) (2R,4,5,6S,7S,8R,9S,9,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)octahydro-2H-benzo[b]pyrano[2,3-e][1,4]dioxin-4(3H)-one hydrochloride Spectinomycin2HClpentahydrate (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-méthyl-6,8-bis(méthylamino)décahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dichlorhydrate 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-Methyl-6,8-bis(MethylaMino)-, hydrochloride(1:2), (2R,4,5,6S,7S,8R,9S,9,10aS) (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dihydrochloride hydrate ACTINOSPECTACIN DIHYDROCHLORIDE SPECTINOMYCIN READY MADE SOLUTION Anti-Bacterial Intermediate SPECTINOMYCIN DIHYDROCHLORIDE //BP SPECTINOMYCIN DIHYDROC 8-beta,9-alpha,9a-alpha,10a-beta))-t SpectinoMycinHydrochloride for Injection 4H-pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, dihydrochloride 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, (2R,4,5,6S,7S,8R,9S,9,10aS)- (9CI) (2R,4,5,6S,7S,8R,9S,9,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)octahydro-2H-benzo[b]pyrano[2,3-e][1,4]dioxin-4(3H)-one HCl 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, hydrochloride, hydrate (1:2:1) Spectinomycin Hydrochlori (2R,4,5,6S,7S,8R,9S,9,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-benzo[b]pyrano[2,3-e][1,4]dioxin-4-one dihydrochloride (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dihydrochloride (2R,4,5,6S,7S,8R,9S,9,10aS)-decahydro-4a,7,9-trihydroxy-2-Methyl-6,8-bis(MethylaMino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one Hydrochloride Methanomycin hydrochloride SPECTINOMYCIN DIHYDROCHLORIDEv SPECTINOMYCIN DIHYDROCHLORIDE SPECTINOMYCIN HYDROCHLORIDE Methomycin hydrochloride Canine Spectinomycin Precursor SPECTINOMYCINHYDROCHLORIDEANHYDROUS SPECTINOMYCIN 2HCL (2R,4,5,6S,7S,8R,9S,9,10aS)-decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one, hydrochloride (1:2) stanilo 8-bis(methylamino)-,dihydrochloride,(2r-(2-alpha,4a-beta,5a-beta,6-beta,7-be Spectinomycin Hydrochloride and Lincomycin Hydrochloride Soluble Powder Spectacomycin 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, hydrochloride (1:2) Raw Material Spectinomycin Dihydrochloride / Spectinomycin HCL Gentamicin hydrochloride

描述	Spectinomycin双盐酸盐是不经肠道的抗生素,由壮观链霉菌制备而来。
相关类别	信号通路 >> 抗感染 >> 细菌天然产物 >> 其他研究领域 >> 感染
参考文献	[1]. Kehrenberg, C. and S. Schwarz, Mutations in 16S rRNA and ribosomal protein S5 associated with high-level spectinomycin resistance in Pasteurella multocida. Antimicrob Agents Chemother, 2007. 51(6): p. 2244-6. [2]. http://www.toku-e.com/Upload/Products/PDS/20120518003891.pdf

密度	1.43g/cm3
沸点	583.1ºC at 760 mmHg
熔点	194ºC
分子式	C₁₄H₂₆Cl₂N₂O₇
分子量	405.271
闪点	306.4ºC
精确质量	404.111694
PSA	129.51000
外观性状	粉末
蒸汽压	5.05E-16mmHg at 25°C
折射率	1.586
储存条件	2-8°C
水溶解性	H2O: 50 mg/mL, clear, faintly yellow

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ0333500

CHEMICAL NAME :: 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis (methylamino)-, dihydrochloride, (2R-(2-alpha,4a-beta,5a-beta,6-beta,7-beta,8- beta,9-alpha,9a-alpha,10a-beta))-

CAS REGISTRY NUMBER :: 21736-83-4

LAST UPDATED :: 199706

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C14-H24-N2-O7.2Cl-H

MOLECULAR WEIGHT :: 405.32

WISWESSER LINE NOTATION :: T C666 BO DO GV IOTJ E1 HQ KM1 LQ MM1 NQ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2020 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,382,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5600 No. of Facilities: 28 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 525 (estimated) No. of Female Employees: 397 (estimated)