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19685-09-7生产厂家

19685-09-7价格

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19685-09-7

19685-09-7结构式
19685-09-7结构式

化源商城直购

中文名 10-羟基喜树碱
英文名 10-Hydroxycamptothecin
中文别名 伊立替康杂质12(伊立替康杂质B)
10-S-羟基喜树碱
(S)-4-乙基-4,9-二羟基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-B]喹啉-3,14-(4H,12H)
(S)-10-HYDROXYLCAMPTOTHECIN /(S)-10-羟基喜树碱
喜树碱10-羟基杂质
10-羟基喜树碱, 来源于红豆杉
喜树果提取物
喜树碱系列/羟基喜树碱/10-羟基喜树碱/羟喜树碱
盐酸伊立替康杂质B
(S)-4-乙基-4,9-二羟基-1H-吡喃并[3',4':6,7]吲哚并[1,2-B]喹啉-3,14(4H,12H)-二酮
10-羟喜树碱
伊立替康相关物质A
(S)-10-Hydroxycamptothecin (S)-10-羟基喜树碱
伊立替康相关物质A 标准品
10-Hydroxy camptothecin 10-羟基喜树碱
10-羟基喜树碱 67-8
伊立替康杂质B
10-HYDROXYCAMPTOTHECIN,DNA TOPOISOMERASE I抑制剂
10 - 羟基喜树碱
伊立替康 杂质 B(伊立替康 相关化合物 A,10-羟基喜树碱)
10-HYDROXYCAMPTOTHECIN 10-羟基喜树碱
(20S)-10-羟基喜树碱
10-羟基喜树碱/羟基喜树碱/(S)-10-羟基喜树碱/(20S)-10-羟基喜树碱
(4S)-4-乙基-4,9-二羟基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-B]喹啉-3,14-(4H,12H)-二酮
10-羟基喜树碱(伊立替康杂质B)
(S)-4-乙基-4,9-二羟基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-b]喹啉-3,14-(4H,12H)-二酮
伊立替康RC A
(S)-4-乙基-4,9-二羟基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-B]喹啉-3,14-(4H,12H)-二酮
(S)-10-羟基喜树碱 19-7
伊立替康相关化合物A
伊立替康-B
伊立替康杂质B(10-羟基喜树碱)
1-羟基喜树碱
羟基喜树碱
10-羟基喜树碱(羟基喜树碱,(20S)-10-羟基喜树碱,(S)-10-羟基喜树碱)
羟基喜数碱
伊立替康杂质12
10-羟基喜树碱,10 MM DMSO 溶液
10-羟基喜树碱(替康类)
英文别名 10-HYDROXY CAMPTOTHECIN (IRINOTECAN IMPURITY B)
HYDROXYCAMPTOTHECIN, 10
(S)-10-Hydroxycamptothecin (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
hydroxy-camptotheci
Irinotecan Related Compound A (10 mg) ((S)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)
hydrate,(s)-dihydroxy
Camptothecin,hydroxy
HYDROCAMPTOTHECINE
Ampule
Irinotecan Impurity B
Camptothecin, 10-hydroxy
10-HydroxycaMptothecin, froM Taxus chinensis
4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4-ethyl-4,9-dihydroxy-,hydrate,(s)-1h-pyrano(3
10-hydroxycamptothecine
(20S)-10-HYDROXYCAMPTOTHECIN
CaMptothecin 10-Hydroxy IMpurity
HCPT
10-HYDROCAMPTOTHECIN
(S)-4-ethyl-4,9-dihydroxy-1H-pyrano
10-hydroxycamptothecin,HT
HYDROXYCAMPTOTHECIN
Camptothecae Acuminatae extract
SN38
Fructus Camptothecae
(S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
CAMPTOTHECIN, 10-HYDROXY-, CAMPTOTHECA ACUMINATA
(4S)-4,9-Dihydroxy-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
10-Hydroxycamptochecin
10-HydroxycaMptothecin, HydroxycaMptothecine
10-HT
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)
10-Hydroxycamptothecine
10-hydroxy-Camptothecin
(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1,2,4,6,8,10,15-htaene-14,18-dione
Hydroxycamptothecin
Irinotecan Related CoMpound A
4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4-ethyl-4,h-pyrano(3
Irinotecan Related Compound A
Irinotecan Impurity 12
HYDROXYCAMPTOTHECIN, 10-(RG)
CaMptothecin IMpurity
HYDROXYCAMPTOTHECIN, 10-(P)
(4S)-9-Hydroxy-4-hydroxy-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Camptotheca acuminata fruit extract
10-hydroxy-CPT
10-Hydroxycamptothecin 19-7
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4,10-dihydroxy-, (4S)
Irinotecan RC A
(S)-10-HYDROXYCAMPTOTHECIN
(s)-10-hydroxycamptothecinhydrate
CAMPTOTHECIN, 10-HYDROXY
(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(4S)-4α-Ethyl-4,9-dihydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
Hydroxycamptothecine
10-Hydroxycamptothecin from Taxus chinensis (Pilg.) Rehder
10-Hydroxy camptothecin
10-OH-camptothecin
(20S)-10-Hydroxycamptothecine
(+/-)-4-ethyl-4,9-dihydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
MFCD00189425
CAMPTOTHECIN, 10-HYDROXY(SH)
(20S)-10-HYDROXYCAMPTOTHECIN (20S)-7-ETHYL-10-HYDROXYCAMPTOTHECIN (S)-10-HYDROXYCAMPTOTHECIN
Hydroxycamptothencine
10-hydroxycamptothecin (TECANS)
密度 1.6±0.1 g/cm3
沸点 820.7±65.0 °C at 760 mmHg
熔点 265-270°C
分子式 C20H16N2O5
分子量 364.351
闪点 450.1±34.3 °C
精确质量 364.105927
PSA 101.65000
LogP 1.32
外观性状 固体;White to Yellow to Orange powder to crystal
蒸汽压 0.0±3.1 mmHg at 25°C
折射率 1.777
储存条件 -20°C Freezer
计算化学

1.疏水参数计算参考值（XlogP）:0.6

2.氢键供体数量:2

3.氢键受体数量:6

4.可旋转化学键数量:1

5.互变异构体数量:3

6.拓扑分子极性表面积:100

7.重原子数量:27

8.表面电荷:0

9.复杂度:774

10.同位素原子数量:0

11.确定原子立构中心数量:1

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ0491700
CAS REGISTRY NUMBER :
19685-09-7
LAST UPDATED :
198305
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H16-N2-O5.H2-O
MOLECULAR WEIGHT :
382.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
104 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
100 ug/L
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 21,492,1986

危险品运输编码 NONH for all modes of transport
海关编码 2934999090
海关编码 2934999090
中文概述 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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