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67655-94-1

67655-94-1结构式

常用中文名：N-[(2S,3R)-3-氨基-2-羟基-5-甲基-1-氧代己基]-L-缬氨酰-L-缬氨酰-L-天冬氨酸
常用英文名：AMASTATIN
CAS号：67655-94-1
分子式：C₂₁H₃₈N₄O₈
分子量：474.54800
发布时间：2018-12-18 11:44:58
更新时间：2024-01-02 12:44:58
Amastatin is a non-toxic inhibitor of aminopeptidase A (Ki = 1 μM) and leucine aminopeptidase. Also acts as a slow-binding, competitive inhibitor of aminopeptidase M. Does not inhibit aminopeptidase B, chymotrypsin, elastase, papain, pepsin, thermolysin, or trypsin.

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中文名	N-[(2S,3R)-3-氨基-2-羟基-5-甲基-1-氧代己基]-L-缬氨酰-L-缬氨酰-L-天冬氨酸
英文名	amastatin
英文别名	amastatin,streptomyces species

密度	1.228g/cm3
沸点	795.1ºC at 760 mmHg
分子式	C₂₁H₃₈N₄O₈
分子量	474.54800
闪点	434.7ºC
精确质量	474.26900
PSA	208.15000
LogP	0.91940
折射率	1.523

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CI9098850

CHEMICAL NAME :: L-Aspartic acid, N-(N-(3-amino-2-hydroxy-5-methyl-1-oxohexyl)-L-valyl) -L-valyl)-, (S-(R*,S*))-

CAS REGISTRY NUMBER :: 67655-94-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H38-N4-O8

MOLECULAR WEIGHT :: 474.63

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 31,636,1978

危害码 (欧洲)	Xi

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