英文名 | 2,6-bis(4-methoxyphenyl)pyran-4-one |
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英文别名 |
2,6-bis-(4-methoxy-phenyl)-pyran-4-one
4H-Pyran-4-one,2,6-bis(p-methoxyphenyl) 2,6-bis(4-methoxyphenyl)-4H-pyran-4-one 2.6-Bis-<4-methoxy-phenyl>-4-pyron 2,6-Bis-(4-methoxy-phenyl)-pyran-4-on 2,6-di-(4-methoxyphenyl)-4H-pyran-4-one 2.6-Di-<4-methoxy-phenyl>-4-pyron |
描述 | NSC81111是一种有效的口服EGFR-TK抑制剂,IC50为0.15 nM。NSC81111具有抗癌作用[1]。 |
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相关类别 | |
靶点 |
IC50: 0.15 nM (EGFR-TK)[1] |
参考文献 |
密度 | 1.218g/cm3 |
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沸点 | 528.3ºC at 760mmHg |
分子式 | C19H16O4 |
分子量 | 308.32800 |
闪点 | 235.1ºC |
精确质量 | 308.10500 |
PSA | 48.67000 |
LogP | 3.99100 |
蒸汽压 | 3.01E-11mmHg at 25°C |
折射率 | 1.597 |
~84% 1678-14-4 |
文献:Knight, John D.; Metz, Clyde R.; Beam, Charles F.; Pennington, William T.; VanDerveer, Donald G. Synthetic Communications, 2008 , vol. 38, # 14 p. 2465 - 2482 |
~21% 1678-14-4 |
文献:Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966 |
~% 1678-14-4 |
文献:Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966 |
~% 1678-14-4 |
文献:Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966 |
~% 1678-14-4 |
文献:El-Kholy et al. Journal of the Chemical Society, 1959 , p. 2588,2591 |
上游产品 5 | |
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下游产品 2 | |