13073-96-6

• 常用中文名：盐酸去氯羟嗪
• 常用英文名：Decloxizine (dihydrochloride)
• CAS号：13073-96-6
• 分子式：C₂₁H₃₀Cl₂N₂O₂
• 分子量：413.38100
• 相关类别： 原料药 抗变态反应药 抗组胺药
• 发布时间：2018-05-25 08:00:00
• 更新时间：2026-07-16 11:23:10
• Decloxizine(UCB-1402; NSC289116)二盐酸盐1型组胺受体H1拮抗剂。

名称

• 中文名: 盐酸克喘嗪
• 英文名: 2-[2-(4-benzhydrylpiperazin-1-yl)ethoxy]ethanol,dihydrochloride
• 中文别名: 盐酸烃嗪杂质2; 去氯羟嗪盐酸盐; 盐酸去氯羟嗪Decloxizine Dihydrochloride; 盐酸羟嗪杂质B; 2-(2-(4-二苯基甲基)哌嗪-1-基)乙氧基)乙醇二盐酸盐; 盐酸去氯羟嗪,10 MM DMSO 溶液; 盐酸羟嗪杂质B二盐酸盐; 2-(2-(4-二苯甲基哌嗪-1-基)乙氧基)乙醇 盐酸盐; 去氯羟嗪二盐酸盐; 盐酸烃嗪杂质; 盐酸克敏嗪; 盐酸克喘羟嗪; 羟嗪杂质B
• 英文别名: Hydroxydiethylphenamine; 2-[2-[4-(Diphenylmethyl)piperazin-1; Decloxizine DiHCl; 2-(2-(4-(Diphenylmethyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride; Decloxizine dihydrochloride, 10 mM in DMSO; Ethanol, 2-(2-(4-(diphenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride; 1-[2-(2-Hydroxyethoxy)ethyl]-4-α-phenylbenzyldiethylenediaMine Dihydrochloride; Hydroxyzine Impurity B (as Dihydrochloride); UCB 1402 dihydrochloride; Hydroxyzine Impurity B; Ethanol, 2-[2-[4-(diphenylmethyl)-1-piperazinyl]ethoxy]-, hydrochloride (1:2); 1-[2-(2-Hydroxyethoxy)ethyl]-4-alpha-phenylbenzyldiethylenediamine dihydrochloride; Hydroxyzine Hydrochloride Impurity B as Dihydrochloride; UCB1402 dihydrochloride; decloxizin hydrochloride; UCB-1402 dihydrochloride; 2-[2-[4-(Diphenylmethyl)piperazin-1-yl]ethoxy]ethanol Dihydrochloride (Decloxizine Dihydrochloride); Rescupal; Hydroxyzine Impurity 2(Hydroxyzine Impurity B); Autok; 2-[2-[4-(DiphenylMethyl)-1-piperazinyl]ethoxy]ethanol Hydrochloride; Decloxizine Dihydrochloride; Hydroxydiethylphenamine //BP; Decloxizine HCl (UCB-1402

物化性质

• 密度: 1.115g/cm3
• 沸点: 472.4ºC at 760mmHg
• 分子式: C₂₁H₃₀Cl₂N₂O₂
• 分子量: 413.38100
• 闪点: 239.5ºC
• 精确质量: 412.16800
• PSA: 35.94000
• LogP: 3.88230
• 蒸汽压: 9.93E-10mmHg at 25°C
• 储存条件: 2-8℃

生物活性

• 描述: Decloxizine(UCB-1402; NSC289116)二盐酸盐1型组胺受体H1拮抗剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
  信号通路 >> 免疫及炎症 >> 组胺受体
  研究领域 >> 炎症/免疫