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Lorglumide钠盐

更新时间:2025-08-26 18:29:41

Lorglumide钠盐结构式
Lorglumide钠盐结构式
品牌特惠专场
常用名 Lorglumide钠盐 英文名 Lorglumide sodium salt
CAS号 1021868-76-7 分子量 481.388
密度 N/A 沸点 N/A
分子式 C22H31Cl2N2NaO4 熔点 N/A
MSDS 中文版 美版 闪点 N/A

 Lorglumide钠盐用途


Lorglumide sodium salt (CR-1409 sodium salt) 是一种有效的胆囊收缩素(CCK)受体拮抗剂。

 Lorglumide钠盐名称

中文名 Lorglumide钠盐
英文名 Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxo-2-butanyl]carbamoyl}-1,2-dichlorobenzene
英文别名 更多

 Lorglumide钠盐生物活性

描述 Lorglumide sodium salt (CR-1409 sodium salt) 是一种有效的胆囊收缩素(CCK)受体拮抗剂。
相关类别
靶点实验

CCK[1]

参考文献

[1]. Scarpignato C, et al. Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat. Br J Pharmacol. 1989 Mar;96(3):661-9.

 Lorglumide钠盐物理化学性质

分子式 C22H31Cl2N2NaO4
分子量 481.388
精确质量 480.155853
储存条件 2-8℃

 Lorglumide钠盐安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
RTECS号 SA3680700

 Lorglumide钠盐文献7

更多文献
Different downstream signalling of CCK1 receptors regulates distinct functions of CCK in pancreatic beta cells.

Br. J. Pharmacol. 172 , 5050-67, (2015)

Cholecystokinin (CCK) is secreted by intestinal I cells and regulates important metabolic functions. In pancreatic islets, CCK controls beta cell functions primarily through CCK1 receptors, but the si...

Involvement of different subtypes of cholecystokinin receptors in opioid antinociception in the mouse.

Peptides 16(7) , 1229-34, (1995)

Various doses of sulfated cholecystokinin octapeptide (CCK-8s) injected intracerebroventricularly (ICV) alone did not show any antinociceptive effect. CCK-8s (0.01-1 ng) pretreated ICV for 10 min dose...

Expression of the transcription factor Egr-1 in pancreatic acinar cells following stimulation of cholecystokinin or Gαq-coupled designer receptors.

Cell Physiol. Biochem. 33(5) , 1411-25, (2014)

BACKGOUND/AIMS: The injection of cerulein, an analogue of the pancreatic secretagogue cholecystokinin (CCK), induces acute pancreatitis in mice that is accompanied by the synthesis of the transcriptio...

 Lorglumide钠盐靶点实验

查看更多实验

实验名称:Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1266185
实验名称:Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源:NCGC
External Id:SNCA-p-activity-luciferase
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
实验名称:qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
来源:NCGC
External Id:HERG01
实验名称:qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
来源:NCGC
靶标:N/A
External Id:SMAD3201
实验名称:uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
来源:Burnham Center for Chemical Genomics
靶标:cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id:SBCCG-A764-CF-PAF-Primary-Assay
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ant...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_ANT_FLUO8_1536_1X%INH PRUN
实验名称:qHTS for Inhibitors of TGF-b
来源:NCGC
靶标:Smad3 [Homo sapiens]
External Id:SMAD3101
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 Lorglumide钠盐英文别名

Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxobutan-2-yl]carbamoyl}-1,2-dichlorobenzene
Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxo-2-butanyl]carbamoyl}-1,2-dichlorobenzene
MFCD00083183
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