ACC1/2-IN-2

• 常用名: ACC1/2-IN-2
• 英文名: ACC1/2-IN-2
• CAS号: 1031411-94-5
• 分子量: 403.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₅N₃O₃
• 熔点: N/A
• 闪点: N/A

ACC1/2-IN-2用途

ACC1/2-IN-1(化合物4s)是一种强效的ACC1/1抑制剂,对ACC1和ACC2的IC50值分别为98.06和29.43 nM。ACC1/2-IN-1可用于癌症研究[1]。

ACC1/2-IN-2名称

• 英文名: ACC1/2-IN-2

ACC1/2-IN-2生物活性

• 描述: ACC1/2-IN-1(化合物4s)是一种强效的ACC1/1抑制剂,对ACC1和ACC2的IC50值分别为98.06和29.43 nM。ACC1/2-IN-1可用于癌症研究[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 代谢酶/蛋白酶 >> 乙酰辅酶A羧化酶
• 参考文献:

  [1]. Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

ACC1/2-IN-2物理化学性质

• 分子式: C₂₄H₂₅N₃O₃
• 分子量: 403.47

ACC1/2-IN-2靶点实验

查看更多实验

实验名称：Intrinsic clearance in human microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL3412277

实验名称：Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by flu... 来源：ChEMBL 靶标：Acetyl-CoA carboxylase 2 External Id：CHEMBL1959087

实验名称：Intrinsic clearance in human liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1959088

实验名称：Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescenc... 来源：ChEMBL 靶标：Acetyl-CoA carboxylase 2 External Id：CHEMBL1115284

实验名称：Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counter 来源：ChEMBL 靶标：Acetyl-CoA carboxylase 1 External Id：CHEMBL1115283

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