克林沙星

更新时间:2024-01-02 10:41:47

克林沙星结构式
克林沙星结构式
品牌特惠专场
常用名 克林沙星 英文名 Clinafloxacin
CAS号 105956-97-6 分子量 365.78700
密度 1.573 g/cm3 沸点 592.3ºC at 760 mmHg
分子式 C17H17ClFN3O3 熔点 253-258ºC
MSDS 中文版 美版 闪点 312ºC
符号 GHS08
GHS08
信号词 Warning

 克林沙星用途


Clinafloxacin(PD-127391)是氟喹诺酮抗生素。

 克林沙星名称

中文名 克林沙星
英文名 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
中文别名 罗非考昔 | 7-(3-氨基-1-吡咯烷基)-1-环丙基-6-氟-8-氯-1,4-二氢-4-氧代-3-喹啉羧酸 | 1-环丙基-6-氟-7-(3-氨基吡咯烷-1-基)-8-氯-1,4-二氢-4-氧-喹啉-3-羧酸
英文别名 更多

 克林沙星物理化学性质

密度 1.573 g/cm3
沸点 592.3ºC at 760 mmHg
熔点 253-258ºC
分子式 C17H17ClFN3O3
分子量 365.78700
闪点 312ºC
精确质量 365.09400
PSA 88.56000
LogP 3.12980
外观性状 白色至淡黄色结晶粉末
蒸汽压 7.14E-15mmHg at 25°C
折射率 1.684
储存条件 2-8°C

 克林沙星安全信息

符号 GHS08
GHS08
信号词 Warning
危害声明 H361d
警示性声明 P281
危害码 (欧洲) Xi
风险声明 (欧洲) R36/37/38
安全声明 (欧洲) S26-S36
危险品运输编码 NONH for all modes of transport
RTECS号 VB1800600
海关编码 2933990090

 克林沙星海关

海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 克林沙星文献28

更多文献
Pharmacokinetics of danofloxacin and N-desmethyldanofloxacin in adult horses and their concentration in synovial fluid.

J. Vet. Pharmacol. Ther. 38(2) , 123-9, (2015)

The objectives of this study were to investigate the pharmacokinetics of danofloxacin and its metabolite N-desmethyldanofloxacin and to determine their concentrations in synovial fluid after administr...

Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones.

J. Antimicrob. Chemother. 52(4) , 605-9, (2003)

Garenoxacin is a novel des-F(6)-quinolone with good anti-anaerobe activity. The accumulation of garenoxacin and five other quinolones in the presence and absence of a variety of efflux pump inhibitors...

Synthesis and antibacterial activity of novel pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid derivatives carrying the 3-cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl group as a C-10 substituent.

J. Med. Chem. 51 , 3238-49, (2008)

Novel pyrido[1,2,3- de][1,4]benzoxazine-6-carboxylic acid derivatives 5- 9 carrying a 3-cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl moiety at the C-10 position were synthesized and their in vi...

 克林沙星英文别名

MFCD00865120
Clinafloxacin
7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
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