坦索洛新

• 常用名: 坦索洛新
• 英文名: Tamsulosin
• CAS号: 106133-20-4
• 分子量: 408.512
• 密度: 1.2±0.1 g/cm3
• 沸点: 595.5±60.0 °C at 760 mmHg
• 分子式: C₂₀H₂₈N₂O₅S
• 熔点: 226-228ºC
• 闪点: 313.9±32.9 °C

坦索洛新用途

Tamsulosin是α1受体拮抗剂。

坦索洛新名称

• 中文名: 坦索洛新
• 英文名: tamsulosin
• 中文别名: (R)-5[2-[2-(2-乙氧基苯氧基)]乙胺基]丙基]-2-甲氧基-苯磺酰胺 | 坦索罗辛2-羟基苯丙酮 | 坦索罗辛 | 盐酸坦索罗辛(盐酸坦洛辛)

坦索洛新生物活性

• 描述: Tamsulosin是α1受体拮抗剂。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Jeong, I.G., et al., Impact of tamsulosin on urinary retention following early catheter removal after robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled trial. Int J Urol, 2014. 21(2): p. 164-8.

  [2]. Lucas, M.G., T.P. Stephenson, and V. Nargund, Tamsulosin in the management of patients in acute urinary retention from benign prostatic hyperplasia. BJU Int, 2005. 95(3): p. 354-7.

坦索洛新物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 595.5±60.0 °C at 760 mmHg
• 熔点: 226-228ºC
• 分子式: C₂₀H₂₈N₂O₅S
• 分子量: 408.512
• 闪点: 313.9±32.9 °C
• 精确质量: 408.171906
• PSA: 108.26000
• LogP: 2.24
• InChIKey: DRHKJLXJIQTDTD-OAHLLOKOSA-N
• SMILES: CCOc1ccccc1OCCNC(C)Cc1ccc(OC)c(S(N)(=O)=O)c1
• 外观性状: 白色晶体
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.553
• 储存条件: 室温，避光干燥密封

坦索洛新安全信息

• 海关编码: 2935009090

坦索洛新海关

• 海关编码: 2935009090
• 中文概述: 2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

坦索洛新靶点实验

查看更多实验

实验名称：Antagonist dissociation equilibrium constant was tested against rat prosta contractio... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL798239

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：Drug activation in human Hep3B cells assessed as human CYP2C9-mediated drug metabolis... 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL4478999

实验名称：Drug activation in human Hep3B cells assessed as human CYP3A4-mediated drug metabolis... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL4479000

实验名称：Compound at 1 uM was tested for the inhibition of radioligand [3H]MK-912 binding to r... 来源：ChEMBL 靶标：Alpha-2C adrenergic receptor External Id：CHEMBL648610

实验名称：Binding affinity to human cloned adrenergic alpha-1d receptor 来源：ChEMBL 靶标：Alpha-1D adrenergic receptor External Id：CHEMBL889237

实验名称：Selectivity ratio against D3 (dopaminergic) receptor 来源：ChEMBL 靶标：D(3) dopamine receptor External Id：CHEMBL845442

实验名称：Selectivity ratio against D2S( dopaminergic) receptor 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL844240

实验名称：Selectivity ratio against D2L (dopaminergic) receptor 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL844239

实验名称：Selectivity ratio against alpha-2a (Adrenergic Receptor-2a) receptor 来源：ChEMBL 靶标：Alpha-2A adrenergic receptor External Id：CHEMBL845445

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坦索洛新英文别名

• amsulosin
• Flomax
• Tamsulosinum
• 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
• [14C]-Tamsulosin
• (R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide
• Tamsulosine
• Tamsulosina
• 5-{(2R)-2-[(2-{[2-(ethyloxy)phenyl]oxy}ethyl)amino]propyl}-2-(methyloxy)benzenesulfonamide
• Tamsulosin
• Tamsolusin
• MFCD00871531
• Tamsulosina [INN-Spanish]
• Tamsulosine [INN-French]
• (R)-(-)-5-[2-(2-(2-ethoxyphenoxy)ethylamino)propyl]-2-methoxybenzenesulfonamide
• 5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide
• Tamsulosinum [INN-Latin]