isoCA-4

• 常用名: isoCA-4
• 英文名: isoCA-4
• CAS号: 1067880-31-2
• 分子量: 316.35
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₀O₅
• 熔点: N/A
• 闪点: N/A

isoCA-4用途

isoCA-4是一种Combrestatin A4衍生物,是一种微管蛋白聚合抑制剂。isoCA-4具有抗增殖活性[1]。

isoCA-4名称

• 英文名: isoCA-4

isoCA-4生物活性

• 描述: isoCA-4是一种Combrestatin A4衍生物,是一种微管蛋白聚合抑制剂。isoCA-4具有抗增殖活性[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
• 参考文献:

  [1]. Xiang-Yu Yan, et al. Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. Eur J Med Chem. 2022 Apr 16;237:114372.

isoCA-4物理化学性质

• 分子式: C₁₈H₂₀O₅
• 分子量: 316.35
• InChIKey: CNGKIRSNRQSORA-UHFFFAOYSA-N
• SMILES: C=C(c1ccc(OC)c(O)c1)c1cc(OC)c(OC)c(OC)c1

isoCA-4靶点实验

查看更多实验

实验名称：Inhibition of sheep brain tubulin polymerization using DAPI by fluorimetry 来源：ChEMBL 靶标：N/A External Id：CHEMBL2343511

实验名称：Anti-tumor activity against mouse H22 cells allografted in ICR mice assessed as reduc... 来源：ChEMBL 靶标：H22 External Id：CHEMBL4769155

实验名称：Anti-tumor activity against mouse H22 cells allografted in ICR mice assessed as reduc... 来源：ChEMBL 靶标：H22 External Id：CHEMBL4769156

实验名称：Displacement of [3H]colchicine from porcine brain tubulin at 5 uM incubated for 2 hrs... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4769138

实验名称：Antiangiogenic activity in human ECFC co-cultured with human ADSC assessed as inhibit... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3239520

实验名称：Displacement of [3H]colchicine from porcine brain tubulin at 1 uM incubated for 2 hrs... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4769137

实验名称：Antiproliferative activity against human U87 cells after 72 hrs by resazurin-based fl... 来源：ChEMBL 靶标：U-87 MG External Id：CHEMBL4143254

实验名称：Antiproliferative activity against human MCF7 cells after 72 hrs by resazurin-based f... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4143255

实验名称：against A against n against t against i against p against r against o against l again... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4769131

实验名称：Antiproliferative activity against human K562R cells after 72 hrs by resazurin-based ... 来源：ChEMBL 靶标：K-562R External Id：CHEMBL4143256

共150条，当前第1页，共15页

1

2

3

4

5