莫西菌素

更新时间：2024-01-02 13:36:36

莫西菌素结构式	常用名	莫西菌素	英文名	Moxidectin
	CAS号	113507-06-5	分子量	639.819
	密度	1.2±0.1 g/cm3	沸点	790.0±70.0 °C at 760 mmHg
	分子式	C₃₇H₅₃NO₈	熔点	132 °C
	MSDS	中文版美版	闪点	431.6±35.7 °C
	符号	GHS06, GHS09	信号词	Danger

莫西菌素用途

Moxidectin(ProHeart 6; CL301423; Cydectin)是驱虫剂,可用于预防和控制心丝虫和蛔虫。

中文名	莫昔克丁
英文名	moxidectin
中文别名	莫西菌素 \| 莫西丁克 \| 莫西克汀
英文别名	更多

描述	Moxidectin(ProHeart 6; CL301423; Cydectin)是驱虫剂,可用于预防和控制心丝虫和蛔虫。
相关类别	信号通路 >> 抗感染 >> 寄生物研究领域 >> 感染
参考文献	[1]. Moxidectin, From Wikipedia

密度	1.2±0.1 g/cm3
沸点	790.0±70.0 °C at 760 mmHg
熔点	132 °C
分子式	C₃₇H₅₃NO₈
分子量	639.819
闪点	431.6±35.7 °C
精确质量	639.377136
PSA	116.04000
LogP	8.43
外观性状	固体;White to Almost white powder to crystal
蒸汽压	0.0±6.2 mmHg at 25°C
折射率	1.581
储存条件	2-8°C

符号	GHS06, GHS09
信号词	Danger
危害声明	H301-H400
警示性声明	Missing Phrase - N15.00950417
个人防护装备	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
危害码 (欧洲)	T,N
风险声明 (欧洲)	25-50
安全声明 (欧洲)	45-61-24/25
危险品运输编码	UN 2588
RTECS号	PY5438800
包装等级	III
危险类别	6.1(b)
海关编码	29322090

甲氧胺盐酸盐

593-56-6

112124-81-9

~81%

莫西菌素

113507-06-5

文献：Tetrahedron Letters, , vol. 29, # 21 p. 2595 - 2598

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113462-09-2

莫西菌素

113507-06-5

文献：Tetrahedron Letters, , vol. 29, # 21 p. 2595 - 2598

108702-57-4

莫西菌素

113507-06-5

文献：Tetrahedron Letters, , vol. 29, # 21 p. 2595 - 2598

Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: "The Worminator".

Int. J. Parasitol. Drugs Drug Resist. 4(3) , 233-43, (2014)

A major hindrance to evaluating nematode populations for anthelmintic resistance, as well as for screening existing drugs, new compounds, or bioactive plant extracts for anthelmintic properties, is th...

In-vitro activity of avermectins against Mycobacterium ulcerans.

PLoS Negl. Trop. Dis. 9(3) , e0003549, (2015)

Mycobacterium ulcerans causes Buruli ulcer (BU), a debilitating infection of subcutaneous tissue. There is a WHO-recommended antibiotic treatment requiring an 8-week course of streptomycin and rifampi...

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.

EMBO Mol. Med. 6(10) , 1263-78, (2014)

Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed...

Equest

Vetdectin Oral Drench

(1'R,2R,4E,4'S,5S,6S,8'R,10'E,13'R,14'E,16'E,20'R,21'R,24'S)-21',24'-Dihydroxy-4-(methoxyimino)-5,11',13',22'-tetramethyl-6-[(2E)-4-methyl-2-penten-2-yl]-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,1 ;9]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-2'-one

proheart

bridged fused ring systems nomenclature: (2aE,4E,8E)-(5’S,6R,6’S,11R,13R,15S,17aR,20R,20aR,20bS)-6’-[(1E)-1,3-dimethylbut-1-enyl]-5’,6’,10,11,14,15,17a,20,20a,20b-decahydro-20,20b-dihydroxy-5’,6,8,19-tetramethylspiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2’-[2H]pyran]-4’,17(3’H,6H)-dione 4’-(E)-(O-methyloxime)

ProHeart 6

Moxidectin HOUSE STANDARD

Moxidectin

(6R,23E,25S)-5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)milbemycin B

Quest

extended von Baeyer nomenclature: (10E,14E,16E)-(1R,4S,5’S,6R,6’S,8R,13R,20R,21R,24S)-6’-[(1E)-1,3-dimethylbut-1-enyl]-21,24-dihydroxy-5’,11,13,22-tetramethyl-(3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene)-6-spiro-2’-(tetrahydropyran)-2,4’-dione 4’-(E)-(O-methyloxime)