奥比沙星结构式
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常用名 | 奥比沙星 | 英文名 | Orbifloxacin |
|---|---|---|---|---|
| CAS号 | 113617-63-3 | 分子量 | 395.376 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 590.7±50.0 °C at 760 mmHg | |
| 分子式 | C19H20F3N3O3 | 熔点 | 260 °C(dec.) | |
| MSDS | 中文版 美版 | 闪点 | 311.1±30.1 °C |
奥比沙星用途Orbifloxacin是一种合成的氟喹诺酮类广谱抗生素,已被批准用于犬类。 |
| 中文名 | 奥比沙星 |
|---|---|
| 英文名 | Orbifloxacin |
| 中文别名 | 1-环丙基-5,6,8-三氟-7-(CIS-3,5-二甲基哌嗪)-1,4-二氢-4-氧-喹啉-3-羧酸 | 三氯苯咪唑 | 1-环丙基-5,6,8-三氟-7-(Cis-3,5-二甲基哌嗪)-1,4-二氢-4-氧-喹啉-3-羧酸 | 1-环丙基-5,6,8-三氟-7-(顺式-3,5-二甲基哌嗪)-1,4-二氢-4-氧代喹啉-3-羧酸 |
| 英文别名 | 更多 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 590.7±50.0 °C at 760 mmHg |
| 熔点 | 260 °C(dec.) |
| 分子式 | C19H20F3N3O3 |
| 分子量 | 395.376 |
| 闪点 | 311.1±30.1 °C |
| 精确质量 | 395.145691 |
| PSA | 74.57000 |
| LogP | 2.37 |
| InChIKey | QIPQASLPWJVQMH-DTORHVGOSA-N |
| SMILES | CC1CN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC(C)N1 |
| 外观性状 | 固体;White to Orange to Green powder to crystal |
| 蒸汽压 | 0.0±1.7 mmHg at 25°C |
| 折射率 | 1.588 |
| 储存条件 | 室温 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
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~72%
奥比沙星 113617-63-3 |
| 文献:Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 - 1656 |
| 奥比沙星上游产品 2 | |
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| 奥比沙星下游产品 0 | |
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Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.
Food Chem. 181 , 119-26, (2015) A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP... |
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Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.
J. AOAC Int. 98(1) , 230-47, (2015) Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ... |
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Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods.
Anal. Bioanal. Chem 406(30) , 7899-910, (2014) Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health... |
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实验名称:Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源:NCGC
External Id:SNCA-p-activity-luciferase
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
来源:824
External Id:CYP273
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
来源:NCGC
External Id:HERG01
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实验名称:uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
来源:Burnham Center for Chemical Genomics
靶标:cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id:SBCCG-A764-CF-PAF-Primary-Assay
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ant...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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实验名称:Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
来源:NCGC
External Id:APP-Toga-CHIKV-nsp2-p
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| 1-cyclopropyl-7-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
| Orbifloxacin |
| 1-cyclopropyl-7-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxoquinoline-3-carboxylic acid |
| Orbax |
| 1-Cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
| MFCD00864858 |